| Title |
Depression in blepharospasm: a question of facial feedback?
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, July 2017
|
| DOI | 10.2147/ndt.s141066 |
| Pubmed ID | |
| Authors |
Janis Rebecca Bedarf, Sied Kebir, Joan Philipp Michelis, Bettina Wabbels, Sebastian Paus |
| Abstract |
Depression is the most important nonmotor symptom in blepharospasm (BL). As facial expression influences emotional perception, summarized as the facial feedback hypothesis, we investigated if patients report fewer depressive symptoms if injections of botulinum neurotoxin (BoNT) include the "grief muscles" of the glabellar region, compared to treatment of orbicularis oculi muscles alone. Ninety BL patients were included, half of whom had BoNT treatment including the frown lines. While treatment pattern did not predict depressive symptoms overall, subgroup analysis revealed that in male BL patients, BoNT injections into the frown lines were associated with remarkably less depressive symptoms. We hypothesize that in BL patients presenting with dystonia of the eyebrow region, BoNT therapy should include frown line application whenever justified, to optimize nonmotor effects of BoNT denervation. |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 28 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 18% |
| Researcher | 4 | 14% |
| Other | 3 | 11% |
| Student > Bachelor | 3 | 11% |
| Student > Doctoral Student | 2 | 7% |
| Other | 3 | 11% |
| Unknown | 8 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 9 | 32% |
| Medicine and Dentistry | 6 | 21% |
| Neuroscience | 2 | 7% |
| Social Sciences | 1 | 4% |
| Nursing and Health Professions | 1 | 4% |
| Other | 0 | 0% |
| Unknown | 9 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 July 2017.
All research outputs
#20,660,571
of 25,382,440 outputs
Outputs from Neuropsychiatric Disease and Treatment
#2,328
of 3,131 outputs
Outputs of similar age
#252,263
of 326,871 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#59
of 92 outputs
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