Title |
Hypertension in pediatric patients with chronic kidney disease: management challenges
|
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Published in |
International Journal of Nephrology and Renovascular Disease, July 2017
|
DOI | 10.2147/ijnrd.s100891 |
Pubmed ID | |
Authors |
Claire M Gallibois, Natasha A Jawa, Damien G Noone |
Abstract |
In contrast to adults where hypertension is a leading cause of chronic kidney disease, in pediatrics, hypertension is predominantly a sequela, however, an important one that, like in adults, is likely associated with a more rapid decline in kidney function or progression of chronic kidney disease to end stage. There is a significant issue with unrecognized, or masked, hypertension in childhood chronic kidney disease. Recent evidence and, therefore, guidelines now suggest targeting a blood pressure of <50th percentile for age, sex, and height in children with proteinuria and chronic kidney disease. This often cannot be achieved by monotherapy and additional agents need to be added. Blockade of the renin angiotensin aldosterone system represents the mainstay of therapy, although often limited by the side effect of hyperkalemia. The addition of a diuretic, at least in the earlier stages of chronic kidney disease, might help mitigate this problem. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 17% |
Peru | 1 | 17% |
United States | 1 | 17% |
Unknown | 3 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 118 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 18 | 15% |
Student > Master | 17 | 14% |
Student > Postgraduate | 9 | 8% |
Other | 6 | 5% |
Student > Doctoral Student | 5 | 4% |
Other | 14 | 12% |
Unknown | 49 | 42% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 35 | 30% |
Nursing and Health Professions | 15 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 4% |
Biochemistry, Genetics and Molecular Biology | 3 | 3% |
Arts and Humanities | 2 | 2% |
Other | 6 | 5% |
Unknown | 52 | 44% |