Title |
Novel biomarkers for prediabetes, diabetes, and associated complications
|
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Published in |
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, August 2017
|
DOI | 10.2147/dmso.s100074 |
Pubmed ID | |
Authors |
Brenda Dorcely, Karin Katz, Ram Jagannathan, Stephanie S Chiang, Babajide Oluwadare, Ira J Goldberg, Michael Bergman |
Abstract |
The number of individuals with prediabetes is expected to grow substantially and estimated to globally affect 482 million people by 2040. Therefore, effective methods for diagnosing prediabetes will be required to reduce the risk of progressing to diabetes and its complications. The current biomarkers, glycated hemoglobin (HbA1c), fructosamine, and glycated albumin have limitations including moderate sensitivity and specificity and are inaccurate in certain clinical conditions. Therefore, identification of additional biomarkers is being explored recognizing that any single biomarker will also likely have inherent limitations. Therefore, combining several biomarkers may more precisely identify those at high risk for developing prediabetes and subsequent progression to diabetes. This review describes recently identified biomarkers and their potential utility for addressing the burgeoning epidemic of dysglycemic disorders. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 389 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 52 | 13% |
Student > Ph. D. Student | 45 | 12% |
Student > Bachelor | 38 | 10% |
Student > Master | 35 | 9% |
Student > Postgraduate | 25 | 6% |
Other | 57 | 15% |
Unknown | 137 | 35% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 73 | 19% |
Medicine and Dentistry | 56 | 14% |
Agricultural and Biological Sciences | 24 | 6% |
Nursing and Health Professions | 22 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 16 | 4% |
Other | 47 | 12% |
Unknown | 151 | 39% |