Title |
Onychomadesis associated with chemotherapy: case report and mini literature review
|
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Published in |
Drug Design, Development and Therapy, August 2017
|
DOI | 10.2147/dddt.s139643 |
Pubmed ID | |
Authors |
Ang Li, Yanqiong Li, Lingzhi Ge, Ping Li, Wenfei Li |
Abstract |
The side effects of chemotherapy drugs have increased in recent years, and some side effects can lead to onychomadesis. A 72-year-old woman who was diagnosed with an invasive ductal carcinoma of the right breast underwent a modified radical mastectomy in April 2015, followed by chemotherapy with capecitabine and nanoparticle albumin-bound paclitaxel (nab-paclitaxel). Subsequently, the patient experienced palmoplantar redness, pain, onycholysis, a transparent serous exudate, and onychomadesis. The chemotherapy was discontinued, and the patient was treated with oral vitamin B6, a polymyxin ointment, and a high-energy red light. The palmoplantar redness and pain were alleviated after 1 month. However, although her fingernails improved, dysesthesia symptoms remained, and all her toenails exhibited defects or deformities at a 24-month follow-up. The symptoms of this disorder should be recognized by dermatologists. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 27 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 4 | 15% |
Other | 3 | 11% |
Lecturer > Senior Lecturer | 2 | 7% |
Student > Ph. D. Student | 2 | 7% |
Student > Bachelor | 2 | 7% |
Other | 4 | 15% |
Unknown | 10 | 37% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 26% |
Nursing and Health Professions | 3 | 11% |
Business, Management and Accounting | 1 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Psychology | 1 | 4% |
Other | 3 | 11% |
Unknown | 11 | 41% |