| Title |
Ionically cross-linked hyaluronic acid: wetting, lubrication, and viscoelasticity of a modified adhesion barrier gel
|
|---|---|
| Published in |
Medical Devices : Evidence and Research, December 2010
|
| DOI | 10.2147/mder.s13962 |
| Pubmed ID | |
| Authors |
Katherine Vorvolakos, Irada S Isayeva, Hoan-My Do Luu, Dinesh V Patwardhan, Steven K Pollack |
| Abstract |
Hyaluronic acid (HA), in linear or cross-linked form, is a common component of cosmetics, personal care products, combination medical products, and medical devices. In all cases, the ability of the HA solution or gel to wet surfaces and/or disrupt and lubricate interfaces is a limiting feature of its mechanism of action. We synthesized ferric ion-cross-linked networks of HA based on an adhesion barrier, varied the degree of cross-linking, and performed wetting goniometry, viscometry, and dynamic mechanical analysis. As cross-linking increases, so do contact angle, viscosity, storage modulus, and loss modulus; thus, wetting and lubrication are compromised. These findings have implications in medical device materials, such as adhesion barriers and mucosal drug delivery vehicles. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| Unknown | 78 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 26% |
| Researcher | 9 | 11% |
| Student > Master | 9 | 11% |
| Student > Bachelor | 6 | 8% |
| Student > Doctoral Student | 5 | 6% |
| Other | 17 | 21% |
| Unknown | 13 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 13 | 16% |
| Agricultural and Biological Sciences | 13 | 16% |
| Medicine and Dentistry | 10 | 13% |
| Materials Science | 9 | 11% |
| Engineering | 6 | 8% |
| Other | 11 | 14% |
| Unknown | 18 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 June 2020.
All research outputs
#7,414,573
of 25,540,105 outputs
Outputs from Medical Devices : Evidence and Research
#92
of 314 outputs
Outputs of similar age
#49,721
of 191,510 outputs
Outputs of similar age from Medical Devices : Evidence and Research
#1
of 3 outputs
Altmetric has tracked 25,540,105 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 314 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.3. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 191,510 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them