Since cellular estrogen surveillance has crucial role in mammary health, either the inhibition of aromatase enzyme activity or estrogen receptor blockage jeopardizes the structural and functional integrity of female breast. https://t.co/zlCUKwGVFz
Since cellular estrogen surveillance has crucial role in mammary health, either the inhibition of aromatase enzyme activity or estrogen receptor blockage jeopardizes the structural and functional integrity of female breast https://t.co/SkDJ3eZtFu
Cellular estrogen surveillance has crucial role in the development and health of female breasts. Either the defect of aromatase enzyme activity or estrogen receptor resistance jeopardizes their structural integrity and functional activity https://t.co/5YoN
When resistance of estrogen receptors is the primary disorder, reactive hyperestrogenism is the predominant hormonal alteration, while patients show clinical signs of weak estrogen signal. https://t.co/Y468dA7E4K
When resistance of estrogen receptors is the primary disorder, reactive hyperestrogenism is the predominant hormonal alteration, while patients show clinical signs of weak estrogen signal. https://t.co/jVqAvwc27r
There was an expectation that studying the correlation between insulin resistance and the defect of gene regulatio https://t.co/B2KDY5alyR
There was an expectation that studying the correlation between insulin resistance and the defect of gene regulatio https://t.co/CraLxWHH4m
In healthy cells, cancer develops via DNA damage, while in cancer cells, DNA restoration results in self directed d https://t.co/WqjS2oWnUT
In postmenopausal women, low estrogen level is the risk for breast cancer, while in premenopausal patients, estroge https://t.co/h4AeQI7spp
Either deficient estrogen receptor activation or estrogen loss in postmenopausal cases in particular may cause incr https://t.co/I1vaaas3GX
When resistance of estrogen receptors is the primary disorder, reactive hyperestrogenism is the predominant hormona https://t.co/jUrBbWYKpX
High estrogen level in insulin resistant breast cancer cases is not a causal factor of tumor but rather a compensat https://t.co/iOnALyANX5
Estrogen is an exceptional hormone as its sky high concentration (in pregnancy) stimulates the whole genomic machin https://t.co/rQT795Fzor
Breast cancer risk is not associated with serum E2 level but rather it depends on the defect of E2 activated ER sig https://t.co/qVMQRRQr9l
High estrogen level alone is not enough to cure breast cancer, but rather sufficient ER expression is also necessar https://t.co/YbHhW2NaiD
All steps of cellular glucose uptake are orchestrated by estrogen signaling, while ER blockade induces insulin resi https://t.co/44wMz2di3E
Defects of estrogen synthesis or ER activation lead to insulin resistance and the associated increased cancer risk. https://t.co/ds1JVD4Vjj
The stronger the estrogen resistance, the higher is the compensatory estrogen level, but it is not always sufficien https://t.co/ikWKGtWDNG
Either insulin resistance or estrogen defect is the primary failure in women, both lead to increased breast cancer https://t.co/X9suqhgnQU
Either decreased estrogen level or resistance of ERs decreases estrogen signal increasing the risk for cancer. https://t.co/UW0YTvF5uq
Defective estrogen signal is the risk of breast cancer instead of an increased serum estrogen level. https://t.co/xxyQOyzP3Z
Both low estrogen level and defective estrogen receptor signal leads to insulin resistance and increased cancer ris https://t.co/W0S0QzMo6J
Defective ER activation is the highest risk of breast cancer instead of an increased level of serum or tissue estro https://t.co/RmgfWKnb2H
Defect in estrogen signaling defines breast cancer risk instead of an increased serum estrogen level. https://t.co/CxTYICAPvf
A defective estrogen signaling is associated with increased cancer risk, in patients either with high or low E2 lev https://t.co/VOVI1fC80r
Either estrogen deficiency or ER resistance are high risks for cancer and cardiovascular diseases https://t.co/n61JTBGhvy
Genomic failures may be initiated via either defect in ER signaling or defect in cellular glucose uptake. https://t.co/THHImGMUlf
Either insulin resistance or defective estrogen signaling may initiate an interplay leading to cancer development. https://t.co/tVLAdw5LZO
The stronger the estrogen resistance, the higher the promising dose of estrogen therapy. https://t.co/FIb67wFLul
The stronger the estrogen resistance, the higher is the promising dose of estrogen therapy for tumors. https://t.co/vzl8sTtVji
Estrogen regulated genes drive all steps of cellular glucose uptake. There is an ER defect behind insulin resistanc https://t.co/eUmbNA5B6K
Estrogen levels and breast cancer risk are not in either direct or inverse correlation but rather a defect in ER si https://t.co/8x17UzReug
Both insulin resistance and defective estrogen signaling may induce cancer development via dysregulation of DNA sta https://t.co/IrsmZamb1C
Estrogen receptor is the highest regulator of genome stability and drives all steps of glucose uptake providing fue https://t.co/pRUxmfzWdy
Estrogen levels are not in direct correlation with cancer risk, but rather a defective estrogen signaling induces c https://t.co/XZNMYa9IJm
Both estrogen deficiency and estrogen resistance induces insulin resistance and an associated increased cancer risk https://t.co/rSmV3zMdf2
Both insulin resistance and defect in estrogen signaling may be an initiator of cancer development. https://t.co/ZqYQjSM7AH
There is no direct correlation between sex steroid levels and breast cancer risk but rather estrogen defect causes https://t.co/TZM0SSK5jQ
There are two kind of defects in estrogen signaling, estrogen deficiency and resistance similarly like diabetes 1-2 https://t.co/LlV1obBsiD
In tumors, the stronger the estrogen resistance, the higher is the promising dose of estrogen therapy. https://t.co/8YPr9a4pOC
Both estrogen deficiency and estrogen resistance are cancer risks quite similarly than type I and type 2 diabetes. https://t.co/PvavzJYuMj
Both estrogen deficiency and estrogen resistance disturb the genomic machinery and increase the risk for cancer. https://t.co/2YDBI5UHGX
Two estrogen diseases are similar to diabetes; both estrogen deficiency and estrogen resistance cause cancer risk. https://t.co/9PgoIPJBvY
Either the inhibition of aromatase enzyme activity or estrogen receptor blockage jeopardizes the structural and fun https://t.co/tAcXpGXJVo
Either the inhibition of aromatase enzyme or estrogen receptor blockage jeopardizes the health of female breast. https://t.co/eaHUYgG2F0
The stronger the estrogen resistance, the higher is the promising dose of estrogen therapy against tumors. https://t.co/69VKcjITXZ
cellular estrogen surveillance has crucial role in mammary health https://t.co/D44vhGZ8G1
The higher the resistance of estrogen receptors, the higher is the promising dose of estrogen for prevention and tr https://t.co/5QwPEuzog0
Both estrogen resistance and insulin resistance may be the initiator of cancer development. https://t.co/9rlrWBK4BV
Increased E2 levels in breast cancer cases are not causal factors, but rather they are compensatory reactions again https://t.co/AsAfieGm16
Defective ER function is the strongest risk of cancer https://t.co/LxPoSxfP0j
Defective estrogen signaling is a high breast cancer risk instead of the increased estrogen concentration https://t.co/G7dX9KJ4jM
There are no direct correlations between estrogen levels and breast cancer risk, but rather the defect of ER signal https://t.co/iv89Zf5Jdz
In breast cancer cases, the stronger the estrogen resistance, the higher is the therapeutic dose of estrogen. https://t.co/5PJ7IsUBca
Neither alterations of ESR genes nor changes in serum estrogen levels may define in themselves the damage of ER sig https://t.co/73pvE9uupA
There are no direct correlations between high estrogen concentrations and breast cancer risk, but rather a defectiv https://t.co/DvtH8gApyU
Upregulation of ER signaling promotes all steps of glucose uptake improving genomic stabilization and apoptosis in https://t.co/MyvWQ9giVP
There are no direct correlations between high estrogen concentrations and breast cancer risk, but rather a defectiv https://t.co/G9IPUdv6B3
There are no direct correlations between high estrogen concentrations and breast cancer risk, but rather a defectiv https://t.co/FkH614QcgV
There are no direct correlations between high estrogen concentrations and breast cancer risk, but rather a defectiv https://t.co/dEpnWRajDv
There is no direct correlation between estrogen level and cancer risk, but rather, the defective ER signaling is th https://t.co/Q51GRikxj4
Neither increased nor decreased estrogen concentration is in direct correlation with breast cancer risk. https://t.co/i1cJmsJmeT
Neither increased nor decreased estrogen level may be directly correlated with breast cancer risk. https://t.co/tQfogYkfpm
Estrogen concentration is not in direct correlation with breast cancer risk, but rather a defective ER signaling in https://t.co/EshjbGx003
Estrogen levels or genetic alterations of ERs in themselves are not in correlation with breast cancer risk, while d https://t.co/v0fOpcmUkb
RT @THYRE15: Insulin resistance and defective estrogen signaling create a vicious circle leading to increased cancer risk. https://t.co/cGv…
Insulin resistance and defective estrogen signaling create a vicious circle leading to increased cancer risk. https://t.co/cGvLdg7So7
Defective ER signaling and insulin resistance create a vicious circle strengthening the risk of cancer. https://t.co/YTM4KXguVc
Insulin resistance and defective estrogen signaling create a vicious circle mutually increasing the risk of breast https://t.co/MsLtqKIgz6
Small genetic defects of ESR1 gene are compensated in young women, while after menopause, decreased estrogen synthe https://t.co/voVdaxsyJa
There is no direct correlation between E2 level and cancer risk, whilst defective ER signaling strongly increases t https://t.co/L2qRw6kaO9
The stronger the estrogen resistance, the higher is the promising dose of estrogen therapy. https://t.co/TDt6cz4swA
Insulin resistance and estrogen deficiency are in mutual correlations causing increased breast cancer risk. https://t.co/4Rg61Ge5id
Estrogen levels are not in direct correlations with breast cancer risk. Either low, or high compensatory level of E https://t.co/4n1FXlhERt
Since cellular estrogen surveillance has crucial role in mammary health, either the inhibition of aromatase enzyme https://t.co/Qnkovx69Zo
ER signaling helps all steps of cellular glucose uptake, while a defective ER action provokes insulin resistance. https://t.co/Kouemwmu9D
Both insulin resistance and ER resistance may induce a vicious circle deteriorating the stabilization of DNA replic https://t.co/OTFuLwHP7Z
Uncompensated estrogen resistance leads to insulin resistance and its comorbidities. https://t.co/BMjRmEfeqj
The stronger the estrogen resistance, the higher is the promising dose of estrogen therapy for restoration of insul https://t.co/Bw9AHRvRFJ
Insulin resistance and defective estrogen signaling create a self generating disturbance of genomic safeguarding. https://t.co/Kp8h7XyR6T
When estrogen resistance is the primary disorder, a compensatory hyperestrogenism is the predominant hormonal alter https://t.co/YXZs2CJ2V1
The stronger the estrogen resistance, the higher is the promising dose of estrogen therapy in breast cancer cases. https://t.co/5s9HfOyUBj
When estrogen resistance is the primary disorder, reactive hyperestrogenism is a defense against the disruption of https://t.co/gMaZvNKuka
Insulin resistance and defective estrogen signaling deteriorate each other in a vicious circle. https://t.co/fHGFS5UJZI
Insulin resistance and defective estrogen signaling creates a vicious circle deteriorating the stabilization of DNA https://t.co/cAeKwdApUq
Both insulin resistance and estrogen deficiency deteriorate genomic stabilization in a vitious circle. https://t.co/sdo8cfWVmW
Appropriate estrogen signaling drives all steps of cellular glucose uptake, while insulin resistance inhibits both https://t.co/l0FIFH6KK7
Both estrogen deficiency and estrogen receptor resistance mean high risk for breast cancer https://t.co/YLt5XUbc2H
Insulin resistance and estrogen signaling defect create a vicious circle leading to tumor development https://t.co/TBkekmCnJ9
Insulin resistance and estrogen deficiency creates a vicious circle deteriorating the somatic and reproductive func https://t.co/BmhAIHcECT
Insulin resistance and deficient estrogen signaling create a self generating vicious circle and increasing tumor ri https://t.co/tmXGC82SrF
Both insulin resistance and defective ER signaling result in disturbances in genom stabilizer machinery. https://t.co/vlA5lsuYrt
Both estrogen deficiency and ER resistance similarly induce defective cellular glucose uptake. https://t.co/L1VMapUXS2
Both estrogen deficiency and ER resistance are in close correlation with insulin resistance. https://t.co/X1vKvanzUs
Both defective estrogen synthesis and resistant estrogen receptors inhibit the glucose uptake conferred by insulin https://t.co/YlDvBBYDYV
The stronger the resistance of estrogen receptors, the higher is the promising dose of estrogen treatment. https://t.co/Ahugi0Mb1D
Estrogen signaling has crucial role in mammary health, either the inhibition of aromatase enzyme activity or estrog https://t.co/qH4DP6foki
Low estrogen concentration induces compensatory high ER expression in tumor cells and results in improved estrogen https://t.co/Iy4nBnBOfB
The higher the resistance of estrogen receptors, the higher is the promising dose of estrogen for prevention and tr https://t.co/I3dlHNDZGK
The higher the resistance of estrogen receptors, the higher is the promising dose of estrogen for prevention and tr https://t.co/gAvy831dF0