| Title |
Host–pathogen interactions and immune evasion strategies in Francisella tularensis pathogenicity
|
|---|---|
| Published in |
Infection and Drug Resistance, September 2014
|
| DOI | 10.2147/idr.s53700 |
| Pubmed ID | |
| Authors |
Don J Steiner, Yoichi Furuya, Dennis W Metzger |
| Abstract |
Francisella tularensis is an intracellular Gram-negative bacterium that causes life-threatening tularemia. Although the prevalence of natural infection is low, F. tularensis remains a tier I priority pathogen due to its extreme virulence and ease of aerosol dissemination. F. tularensis can infect a host through multiple routes, including the intradermal and respiratory routes. Respiratory infection can result from a very small inoculum (ten organisms or fewer) and is the most lethal form of infection. Following infection, F. tularensis employs strategies for immune evasion that delay the immune response, permitting systemic distribution and induction of sepsis. In this review we summarize the current knowledge of F. tularensis in an immunological context, with emphasis on the host response and bacterial evasion of that response. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Sweden | 1 | 1% |
| Unknown | 81 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 19% |
| Researcher | 13 | 16% |
| Student > Bachelor | 12 | 14% |
| Student > Master | 10 | 12% |
| Student > Doctoral Student | 4 | 5% |
| Other | 11 | 13% |
| Unknown | 17 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 23 | 28% |
| Immunology and Microbiology | 17 | 20% |
| Biochemistry, Genetics and Molecular Biology | 11 | 13% |
| Medicine and Dentistry | 4 | 5% |
| Veterinary Science and Veterinary Medicine | 3 | 4% |
| Other | 5 | 6% |
| Unknown | 20 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 September 2014.
All research outputs
#18,379,018
of 22,764,165 outputs
Outputs from Infection and Drug Resistance
#1,013
of 1,633 outputs
Outputs of similar age
#169,012
of 237,235 outputs
Outputs of similar age from Infection and Drug Resistance
#2
of 4 outputs
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