Title |
Omega-3 fatty acid supplementation and cognitive function: are smaller dosages more beneficial?
|
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Published in |
International Journal of General Medicine, September 2014
|
DOI | 10.2147/ijgm.s67065 |
Pubmed ID | |
Authors |
Abdul-Razak Abubakari, Mohammad-Mahdi Naderali, Ebrahim K Naderali |
Abstract |
As longevity increases, so does the global prevalence of cognitive dysfunction. Numerous lifestyle and/or dietary interventions such as omega-3 fatty acids have been suggested to improve memory. Therefore, this study examined the consistency and strength of the impact of supplementation of omega-3 fatty acids on overall cognitive function using systematic reviews and meta-analytic methods. Of 905 studies retrieved from all searches, 12 randomized controlled trials were included in the meta-analysis. There were differences between studies reporting outcomes for single memory function parameters. Subgroup analysis of doses used (low versus high) indicated that subjects receiving low (<1.73 g/day) doses of omega-3 fatty acids had a significant reduction in cognitive decline rate (-0.07, 95% confidence interval -0.01, -0.02) but there was no evidence for beneficial effects at higher doses (+0.04, 95% confidence interval -0.06, +0.14) compared with the placebo group. This study suggests that omega-3 fatty acids may be beneficial in preventing memory decline at lower doses. |
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Geographical breakdown
Country | Count | As % |
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United States | 2 | 50% |
Italy | 1 | 25% |
India | 1 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Spain | 1 | 1% |
Brazil | 1 | 1% |
Unknown | 76 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 13 | 17% |
Researcher | 11 | 14% |
Student > Master | 11 | 14% |
Student > Ph. D. Student | 8 | 10% |
Other | 4 | 5% |
Other | 11 | 14% |
Unknown | 20 | 26% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 17 | 22% |
Nursing and Health Professions | 8 | 10% |
Psychology | 7 | 9% |
Biochemistry, Genetics and Molecular Biology | 6 | 8% |
Agricultural and Biological Sciences | 5 | 6% |
Other | 12 | 15% |
Unknown | 23 | 29% |