Title |
A rare case of lung carcinoma acquires multidrug-resistant Klebsiella pneumoniae pneumonia radiologically mimicking metastasis caused by nivolumab therapy-associated neutropenia
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Published in |
Therapeutics and Clinical Risk Management, October 2017
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DOI | 10.2147/tcrm.s144681 |
Pubmed ID | |
Authors |
Chao Liu, Ling Ding, Ye-han Zhu, Cheng Chen |
Abstract |
Nosocomial infections by Klebsiella pneumoniae, especially those due to multidrug-resistant strains, are being increasingly detected. In this report, we present the case of a 63-year-old man with lung squamous carcinoma who received nivolumab therapy due to failure of first-line chemotherapy. This report also demonstrates an association of nivolumab therapy and neutropenia, and supports the use of a combination of tigecycline and meropenem in managing hospitalization-acquired pneumonia caused by multidrug-resistant K. pneumoniae. It also implicates that a further evaluation is required in lung cancer patients with a suspected metastatic or recurrent carcinoma, and an antibiotic therapy is valuable in ruling out a potential lung infection since a risk of hospitalization-acquired pneumonia may exist. |
X Demographics
Geographical breakdown
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Australia | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 6 | 25% |
Student > Master | 3 | 13% |
Student > Doctoral Student | 2 | 8% |
Other | 2 | 8% |
Student > Postgraduate | 1 | 4% |
Other | 0 | 0% |
Unknown | 10 | 42% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 9 | 38% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 13% |
Unknown | 12 | 50% |