| Title |
Lipoprotein ratios: Physiological significance and clinical usefulness in cardiovascular prevention
|
|---|---|
| Published in |
Vascular Health and Risk Management, September 2009
|
| DOI | 10.2147/vhrm.s6269 |
| Pubmed ID | |
| Authors |
Jesús Millán, Xavier Pintó, Anna Muñoz, Manuel Zúñiga, Joan Rubiés-Prat, Luis Felipe Pallardo, Luis Masana, Alipio Mangas, Antonio Hernández-Mijares, Pedro González-Santos, Juan F Ascaso, Juan Pedro-Botet |
| Abstract |
Low-density lipoprotein (LDL) cholesterol concentration has been the prime index of cardiovascular disease risk and the main target for therapy. However, several lipoprotein ratios or "atherogenic indices" have been defined in an attempt to optimize the predictive capacity of the lipid profile. In this review, we summarize their pathophysiological aspects, and highlight the rationale for using these lipoprotein ratios as cardiovascular risk factors in clinical practice, specifying their cut-off risk levels and a target for lipid-lowering therapy. Total/high-density lipoprotein (HDL) cholesterol and LDL/HDL cholesterol ratios are risk indicators with greater predictive value than isolated parameters used independently, particularly LDL. Future recommendations regarding the diagnosis and treatment of dyslipidemia, including instruments for calculating cardiovascular risk or action guidelines, should include the lipoprotein ratios with greater predictive power which, in view of the evidence-based results, are none other than those which include HDL cholesterol. |
X Demographics
The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 18% |
| Brazil | 2 | 18% |
| Australia | 1 | 9% |
| Ireland | 1 | 9% |
| Spain | 1 | 9% |
| Unknown | 4 | 36% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 82% |
| Scientists | 1 | 9% |
| Practitioners (doctors, other healthcare professionals) | 1 | 9% |
Mendeley readers
The data shown below were compiled from readership statistics for 571 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 3 | <1% |
| Mexico | 2 | <1% |
| India | 1 | <1% |
| Spain | 1 | <1% |
| Bosnia and Herzegovina | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 562 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 81 | 14% |
| Student > Ph. D. Student | 72 | 13% |
| Student > Master | 72 | 13% |
| Researcher | 61 | 11% |
| Other | 42 | 7% |
| Other | 121 | 21% |
| Unknown | 122 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 160 | 28% |
| Agricultural and Biological Sciences | 68 | 12% |
| Biochemistry, Genetics and Molecular Biology | 59 | 10% |
| Nursing and Health Professions | 39 | 7% |
| Sports and Recreations | 28 | 5% |
| Other | 66 | 12% |
| Unknown | 151 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 72. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 July 2023.
All research outputs
#589,901
of 25,371,288 outputs
Outputs from Vascular Health and Risk Management
#19
of 804 outputs
Outputs of similar age
#1,388
of 102,312 outputs
Outputs of similar age from Vascular Health and Risk Management
#1
of 11 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 804 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.3. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 102,312 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.