Title |
Clinical efficacy and safety of statins in managing cardiovascular risk
|
---|---|
Published in |
Vascular Health and Risk Management, April 2008
|
DOI | 10.2147/vhrm.s1653 |
Pubmed ID | |
Authors |
Navin K Kapur, Kiran Musunuru |
Abstract |
Since their introduction in the 1980s, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) have emerged as the one of the best-selling medication classes to date, with numerous trials demonstrating powerful efficacy in preventing cardiovascular outcomes. As our understanding of low-density lipoprotein cholesterol (LDL-C) and atherosclerosis continues to grow, the concept of 'lower is better' has corresponded with a more is better' approach to statin-based therapy. This review provides a detailed understanding of the clinical efficacy and safety of statins with a particular emphasis on the third generation drug, rosuvastatin. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Namibia | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Colombia | 1 | <1% |
Poland | 1 | <1% |
Unknown | 173 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 37 | 21% |
Student > Master | 36 | 21% |
Student > Ph. D. Student | 23 | 13% |
Researcher | 18 | 10% |
Student > Postgraduate | 10 | 6% |
Other | 23 | 13% |
Unknown | 28 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 49 | 28% |
Pharmacology, Toxicology and Pharmaceutical Science | 28 | 16% |
Agricultural and Biological Sciences | 24 | 14% |
Biochemistry, Genetics and Molecular Biology | 17 | 10% |
Nursing and Health Professions | 4 | 2% |
Other | 23 | 13% |
Unknown | 30 | 17% |