Title |
Therapy of an incomplete spinal cord injury by intrathecal injection of EPO and subcutaneous injection of EPO, vitamin C and G-CSF
|
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Published in |
Therapeutics and Clinical Risk Management, November 2017
|
DOI | 10.2147/tcrm.s130627 |
Pubmed ID | |
Authors |
Augustinus Bader, Martin Reinhardt, Achim Beuthe, Klaus Röhl, Shibashish Giri |
Abstract |
Spinal cord injury is a rare disease with an incidence about 40 cases per million population in the USA. The most common reasons are traffic accidents, falls, violence and sports. A 53-year-old male patient presented with an incomplete tetraparesis as a result of a spinal cord injury after the accident. It was not possible to treat him with steroids because he was out of the therapeutic time period of 8 hours when he presented to the hospital. The main problem of spinal cord injuries is the secondary injury caused by inflammation and swelling of the spinal cord. To avoid this, the patient was experimentally treated with erythropoietin (EPO) intrathecal and EPO, granulocyte-colony-stimulating factor and vitamin C subcutaneous after his initial spinal cord relief surgery. These drugs might be able to relieve this secondary reaction but were never applied for this indication in human before. This study shows that it could be a promising treatment for spinal cord injuries with potential therapeutic benefits. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Germany | 2 | 40% |
United States | 2 | 40% |
Unknown | 1 | 20% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 40% |
Science communicators (journalists, bloggers, editors) | 1 | 20% |
Scientists | 1 | 20% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
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Unknown | 34 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 8 | 24% |
Researcher | 5 | 15% |
Student > Master | 3 | 9% |
Professor > Associate Professor | 2 | 6% |
Student > Bachelor | 1 | 3% |
Other | 4 | 12% |
Unknown | 11 | 32% |
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Medicine and Dentistry | 8 | 24% |
Neuroscience | 3 | 9% |
Nursing and Health Professions | 3 | 9% |
Psychology | 2 | 6% |
Biochemistry, Genetics and Molecular Biology | 1 | 3% |
Other | 5 | 15% |
Unknown | 12 | 35% |