| Title |
Biokinetics of zinc oxide nanoparticles: toxicokinetics, biological fates, and protein interaction
|
|---|---|
| Published in |
International Journal of Nanomedicine, December 2014
|
| DOI | 10.2147/ijn.s57920 |
| Pubmed ID | |
| Authors |
Seong Soo An, Soo-Jin Choi, Jin-Ho Choy |
| Abstract |
Biokinetic studies of zinc oxide (ZnO) nanoparticles involve systematic and quantitative analyses of absorption, distribution, metabolism, and excretion in plasma and tissues of whole animals after exposure. A full understanding of the biokinetics provides basic information about nanoparticle entry into systemic circulation, target organs of accumulation and toxicity, and elimination time, which is important for predicting the long-term toxic potential of nanoparticles. Biokinetic behaviors can be dependent on physicochemical properties, dissolution property in biological fluids, and nanoparticle-protein interaction. Moreover, the determination of biological fates of ZnO nanoparticles in the systemic circulation and tissues is critical in interpreting biokinetic behaviors and predicting toxicity potential as well as mechanism. This review focuses on physicochemical factors affecting the biokinetics of ZnO nanoparticles, in concert with understanding bioavailable fates and their interaction with proteins. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 104 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Poland | 1 | <1% |
| Unknown | 102 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 17 | 16% |
| Student > Bachelor | 13 | 13% |
| Researcher | 11 | 11% |
| Student > Doctoral Student | 11 | 11% |
| Student > Master | 10 | 10% |
| Other | 20 | 19% |
| Unknown | 22 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 17 | 16% |
| Biochemistry, Genetics and Molecular Biology | 12 | 12% |
| Medicine and Dentistry | 12 | 12% |
| Chemistry | 11 | 11% |
| Materials Science | 7 | 7% |
| Other | 19 | 18% |
| Unknown | 26 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 January 2015.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from International Journal of Nanomedicine
#3,127
of 4,123 outputs
Outputs of similar age
#274,275
of 369,122 outputs
Outputs of similar age from International Journal of Nanomedicine
#43
of 65 outputs
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