| Title |
Migraine in young females with irritable bowel syndrome: still a challenge
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, December 2017
|
| DOI | 10.2147/ndt.s144955 |
| Pubmed ID | |
| Authors |
Doina Georgescu, Daniela Reisz, Camelia Vidita Gurban, Liviu Andrei Georgescu, Ioana Ionita, Oana Elena Ancusa, Daniel Lighezan |
| Abstract |
Migraine without aura is frequently reported in female patients with irritable bowel syndrome (IBS), but knowledge about the relationship between these two conditions is still lacking. This study was aimed to explore the particularities of migraine without aura in young female patients with IBS in order to establish a possible link between them. From a cohort of young female patients hospitalized with IBS in the Internal Medicine Department, 30 joined this pilot study, and they were assigned into two groups on the basis of presence or absence of migraine. In this sample, 15 patients have mild to moderate migraine without aura, with a recently taken normal brain scan, and 15 were without migraine. Diseases and conditions not related to migraine and other possible specific female comorbidities were ruled out. Patients undertook a thorough clinical examination in order to assess fibromyalgia (FM) and chronic pelvic pain (CPP), Questionnaires for migraine disability assessment (MIDAS) and generalized anxiety disorder (GAD) were performed. Laboratory testing of blood, urine, and stool were also performed. Optimized lymphocyte proliferation test for food allergy (FA) and a fecal microbiota (microbiological semiquantitative method) for dysbiosis (DB) assessment were performed. Based on the results, migraine-positive group displayed more severe comorbidities: FM (p=0.0002), FA (p=0.0006), CPP (p=0.026), higher scores of anxiety (GAD, p=0.0008), and more severe DB (p=0.0009). We noticed a strong positive correlation between MIDAS and GAD (r=0.83), a good positive correlation between MIDAS and DB (r=0.56), and a moderate positive correlation between MIDAS, FM, and FA (r=0.46 and 0.41). In conclusion, young female patients with IBS and migraine without aura displayed more severe associated issues - anxiety, intestinal DB, FM, FA, and CPP. The severity of migraine correlated well with anxiety range and DB magnitude and moderately with FM and FA. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 33% |
| Germany | 1 | 17% |
| Unknown | 3 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Scientists | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 94 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 15 | 16% |
| Researcher | 13 | 14% |
| Other | 8 | 9% |
| Student > Master | 7 | 7% |
| Student > Ph. D. Student | 6 | 6% |
| Other | 13 | 14% |
| Unknown | 32 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 25 | 27% |
| Nursing and Health Professions | 8 | 9% |
| Neuroscience | 5 | 5% |
| Psychology | 5 | 5% |
| Agricultural and Biological Sciences | 4 | 4% |
| Other | 12 | 13% |
| Unknown | 35 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 78. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 May 2022.
All research outputs
#548,868
of 25,382,440 outputs
Outputs from Neuropsychiatric Disease and Treatment
#68
of 3,131 outputs
Outputs of similar age
#12,367
of 444,941 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#4
of 67 outputs
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We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.