| Title |
Frontal brain dysfunction in alcoholism with and without antisocial personality disorder
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, May 2009
|
| DOI | 10.2147/ndt.s4882 |
| Pubmed ID | |
| Authors |
Marlene Oscar-Berman, Mary M Valmas, Kayle S Sawyer, Shalene M Kirkley, David A Gansler, Diane Merritt, Ashley Couture |
| Abstract |
Alcoholism and antisocial personality disorder (ASPD) often are comorbid conditions. Alcoholics, as well as nonalcoholic individuals with ASPD, exhibit behaviors associated with prefrontal brain dysfunction such as increased impulsivity and emotional dysregulation. These behaviors can influence drinking motives and patterns of consumption. Because few studies have investigated the combined association between ASPD and alcoholism on neuropsychological functioning, this study examined the influence of ASPD symptoms and alcoholism on tests sensitive to frontal brain deficits. The participants were 345 men and women. Of them, 144 were abstinent alcoholics (66 with ASPD symptoms), and 201 were nonalcoholic control participants (24 with ASPD symptoms). Performances among the groups were examined with Trails A and B tests, the Wisconsin Card Sorting Test, the Controlled Oral Word Association Test, the Ruff Figural Fluency Test, and Performance subtests of the Wechsler Adult Intelligence Scale. Measures of affect also were obtained. Multiple regression analyses showed that alcoholism, specific drinking variables (amount and duration of heavy drinking), and ASPD were significant predictors of frontal system and affective abnormalities. These effects were different for men and women. The findings suggested that the combination of alcoholism and ASPD leads to greater deficits than the sum of each. |
Mendeley readers
The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 1% |
| United States | 1 | 1% |
| Canada | 1 | 1% |
| Unknown | 67 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 12 | 17% |
| Student > Bachelor | 11 | 16% |
| Student > Ph. D. Student | 9 | 13% |
| Researcher | 7 | 10% |
| Professor > Associate Professor | 5 | 7% |
| Other | 13 | 19% |
| Unknown | 13 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 37 | 53% |
| Neuroscience | 5 | 7% |
| Agricultural and Biological Sciences | 4 | 6% |
| Medicine and Dentistry | 4 | 6% |
| Social Sciences | 3 | 4% |
| Other | 4 | 6% |
| Unknown | 13 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 March 2021.
All research outputs
#8,534,528
of 25,371,288 outputs
Outputs from Neuropsychiatric Disease and Treatment
#1,151
of 3,132 outputs
Outputs of similar age
#36,974
of 104,030 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#2
of 5 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,132 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one has gotten more attention than average, scoring higher than 60% of its peers.
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We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.