Title |
Pharmacological management of acute bronchiolitis
|
---|---|
Published in |
Therapeutics and Clinical Risk Management, October 2008
|
DOI | 10.2147/tcrm.s1556 |
Pubmed ID | |
Authors |
Melvin Wright, Charles J Mullett, Giovanni Piedimonte |
Abstract |
This article reviews the current knowledge base related to the pharmacological treatments for acute bronchiolitis. Bronchiolitis is a common lower respiratory illness affecting infants worldwide. The mainstays of therapy include airway support, supplemental oxygen, and support of fluids and nutrition. Frequently tried pharmacological interventions, such as ribavirin, nebulized bronchodilators, and systemic corticosteroids, have not been proven to benefit patients with bronchiolitis. Antibiotics do not improve the clinical course of patients with bronchiolitis, and should be used only in those patients with proven concurrent bacterial infection. Exogenous surfactant and heliox therapy also cannot be recommended for routine use, but surfactant replacement holds promise and should be further studied. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 2% |
Egypt | 1 | 2% |
Unknown | 50 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 8 | 15% |
Student > Postgraduate | 7 | 13% |
Student > Master | 6 | 12% |
Student > Doctoral Student | 4 | 8% |
Student > Ph. D. Student | 4 | 8% |
Other | 13 | 25% |
Unknown | 10 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 22 | 42% |
Nursing and Health Professions | 6 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 8% |
Chemical Engineering | 1 | 2% |
Immunology and Microbiology | 1 | 2% |
Other | 3 | 6% |
Unknown | 15 | 29% |