| Title |
Emergence and spread of worldwide Staphylococcus aureus clones among cystic fibrosis patients
|
|---|---|
| Published in |
Infection and Drug Resistance, February 2018
|
| DOI | 10.2147/idr.s153427 |
| Pubmed ID | |
| Authors |
Katarzyna Garbacz, Lidia Piechowicz, Magdalena Podkowik, Aneta Mroczkowska, Joanna Empel, Jacek Bania |
| Abstract |
The aim of this study was to assess the relatedness of molecular types ofStaphylococcus aureusisolates colonizing cystic fibrosis (CF) patients with their antimicrobial resistance and prevalence of toxin genes. A total of 215 isolates from the airways of 107 patients with CF were tested forspaand SCCmectype, antimicrobial resistance and carriage of toxin genes. t015, t084, t091, t700 and t002 were the largest group (approximately 25%) among all 69 identified spa types. Five new spa types, t14286, t14287, t14288, t14289 and t14290, were identified and registered. Isolates from CF patients were clustered into 11 multi-locus sequence typing clonal complexes, with CC30, CC22, CC97, CC45, CC15 and CC5 being the most frequent ones. Twelve (5.6%) methicillin-resistantS. aureus(MRSA) isolates and 102 (47.7%) multidrug-resistant isolates were identified, along with three SCCmectypes (I, III and V). All isolates (both MRSA and methicillin-sensitiveS. aureus) were Panton-Valentine leucocidin-negative, and 56.7% harbored egc genes. This was the first study documenting the presence of ST398-V-t571 livestock-associated MRSA in a European patient with CF. These findings imply that individuals with CF can also be colonized with animal-related ST398 MRSA, and justify constant monitoring of staphylococcal colonization and identification of epidemicS. aureusclones in this group. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 2 | 50% |
| Members of the public | 2 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 53 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 15% |
| Student > Ph. D. Student | 7 | 13% |
| Student > Doctoral Student | 7 | 13% |
| Other | 4 | 8% |
| Student > Bachelor | 3 | 6% |
| Other | 8 | 15% |
| Unknown | 16 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 9 | 17% |
| Immunology and Microbiology | 9 | 17% |
| Agricultural and Biological Sciences | 6 | 11% |
| Biochemistry, Genetics and Molecular Biology | 5 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
| Other | 3 | 6% |
| Unknown | 20 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 March 2018.
All research outputs
#8,618,954
of 25,584,565 outputs
Outputs from Infection and Drug Resistance
#379
of 2,048 outputs
Outputs of similar age
#162,843
of 450,135 outputs
Outputs of similar age from Infection and Drug Resistance
#7
of 37 outputs
Altmetric has tracked 25,584,565 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,048 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 450,135 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.