| Title |
Coprescribing proton-pump inhibitors with nonsteroidal anti-inflammatory drugs: risks versus benefits
|
|---|---|
| Published in |
Journal of Pain Research, February 2018
|
| DOI | 10.2147/jpr.s156938 |
| Pubmed ID | |
| Authors |
Kok Ann Gwee, Vernadine Goh, Graca Lima, Sajita Setia |
| Abstract |
Nonsteroidal anti-inflammatory drugs (NSAIDs) are often coadministered with proton-pump inhibitors (PPIs) to reduce NSAID-induced gastrointestinal (GI) adverse events. This coadministration is generally regarded as safe, and is included in many of the guidelines on NSAID prescription. However, recent evidence indicates that the GI risks associated with NSAIDs can be potentiated when they are combined with PPIs. This review discusses the GI effects and complications of NSAIDs and how PPIs may potentiate these effects, options for prevention of GI side effects, and appropriate use of PPIs in combination with NSAIDs. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Paraguay | 1 | 14% |
| Serbia | 1 | 14% |
| United Kingdom | 1 | 14% |
| Unknown | 4 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 191 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 191 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 25 | 13% |
| Student > Master | 21 | 11% |
| Researcher | 13 | 7% |
| Student > Postgraduate | 12 | 6% |
| Other | 8 | 4% |
| Other | 31 | 16% |
| Unknown | 81 | 42% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 40 | 21% |
| Pharmacology, Toxicology and Pharmaceutical Science | 27 | 14% |
| Biochemistry, Genetics and Molecular Biology | 8 | 4% |
| Veterinary Science and Veterinary Medicine | 7 | 4% |
| Nursing and Health Professions | 6 | 3% |
| Other | 17 | 9% |
| Unknown | 86 | 45% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2023.
All research outputs
#2,023,422
of 23,660,057 outputs
Outputs from Journal of Pain Research
#245
of 1,819 outputs
Outputs of similar age
#49,275
of 443,062 outputs
Outputs of similar age from Journal of Pain Research
#7
of 39 outputs
Altmetric has tracked 23,660,057 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,819 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.9. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 443,062 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.