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Adiponectin as a potential biomarker of vascular disease

Overview of attention for article published in Vascular Health and Risk Management, January 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

news
1 news outlet
twitter
2 X users
video
1 YouTube creator

Citations

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93 Dimensions

Readers on

mendeley
157 Mendeley
Title
Adiponectin as a potential biomarker of vascular disease
Published in
Vascular Health and Risk Management, January 2015
DOI 10.2147/vhrm.s48753
Pubmed ID
Authors

Mehrangiz Ebrahimi-Mamaeghani, Somayeh Mohammadi, Seyed Rafie Arefhosseini, Parviz Fallah, Zahra Bazi

Abstract

The increasing prevalence of diabetes and its complications heralds an alarming situation worldwide. Obesity-associated changes in circulating adiponectin concentrations have the capacity to predict insulin sensitivity and are a link between obesity and a number of vascular diseases. One obvious consequence of obesity is a decrease in circulating levels of adiponectin, which are associated with cardiovascular disorders and associated vascular comorbidities. Human and animal studies have demonstrated decreased adiponectin to be an independent risk factor for cardiovascular disease. However, in animal studies, increased circulating adiponectin alleviates obesity-induced endothelial dysfunction and hypertension, and also prevents atherosclerosis, myocardial infarction, and diabetic cardiac tissue disorders. Further, metabolism of a number of foods and medications are affected by induction of adiponectin. Adiponectin has beneficial effects on cardiovascular cells via its antidiabetic, anti-inflammatory, antioxidant, antiapoptotic, antiatherogenic, vasodilatory, and antithrombotic activity, and consequently has a favorable effect on cardiac and vascular health. Understanding the molecular mechanisms underlying the regulation of adiponectin secretion and signaling is critical for designing new therapeutic strategies. This review summarizes the recent evidence for the physiological role and clinical significance of adiponectin in vascular health, identification of the receptor and post-receptor signaling events related to the protective effects of the adiponectin system on vascular compartments, and its potential use as a target for therapeutic intervention in vascular disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 157 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 156 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 26 17%
Student > Master 20 13%
Researcher 18 11%
Student > Ph. D. Student 17 11%
Student > Doctoral Student 15 10%
Other 29 18%
Unknown 32 20%
Readers by discipline Count As %
Medicine and Dentistry 46 29%
Biochemistry, Genetics and Molecular Biology 21 13%
Agricultural and Biological Sciences 20 13%
Nursing and Health Professions 6 4%
Pharmacology, Toxicology and Pharmaceutical Science 5 3%
Other 17 11%
Unknown 42 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2022.
All research outputs
#3,080,895
of 25,374,647 outputs
Outputs from Vascular Health and Risk Management
#96
of 804 outputs
Outputs of similar age
#40,772
of 359,538 outputs
Outputs of similar age from Vascular Health and Risk Management
#4
of 11 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 804 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.3. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 359,538 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.