| Title |
The patterns of toxicity and management of acute nonsteroidal anti-inflammatory drug (NSAID) overdose
|
|---|---|
| Published in |
Open access emergency medicine OAEM, July 2011
|
| DOI | 10.2147/oaem.s22795 |
| Pubmed ID | |
| Authors |
Laura J Hunter, David M Wood, Paul I Dargan |
| Abstract |
The nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for their analgesic, anti-inflammatory and antipyretic actions. They are commonly taken in overdose in many areas of the world. The majority of patients with acute NSAID overdose will remain asymptomatic or develop minor self-limiting gastrointestinal symptoms. However, serious clinical sequelae have been reported in patients with acute NSAID overdose and these include convulsions, metabolic acidosis, coma and acute renal failure. There appear to be some differences between the NSAIDs in terms of the relative risk of these complications; in particular mefenamic acid is most commonly associated with convulsions. The management of these serious clinical features is largely supportive and there are no specific antidotes for acute NSAID toxicity. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 195 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 195 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 25 | 13% |
| Student > Postgraduate | 16 | 8% |
| Student > Master | 15 | 8% |
| Researcher | 14 | 7% |
| Student > Ph. D. Student | 12 | 6% |
| Other | 35 | 18% |
| Unknown | 78 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 45 | 23% |
| Pharmacology, Toxicology and Pharmaceutical Science | 29 | 15% |
| Agricultural and Biological Sciences | 8 | 4% |
| Chemistry | 7 | 4% |
| Biochemistry, Genetics and Molecular Biology | 6 | 3% |
| Other | 19 | 10% |
| Unknown | 81 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 June 2023.
All research outputs
#15,890,095
of 25,603,577 outputs
Outputs from Open access emergency medicine OAEM
#128
of 231 outputs
Outputs of similar age
#88,753
of 127,530 outputs
Outputs of similar age from Open access emergency medicine OAEM
#1
of 1 outputs
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