| Title |
Opioid rotation with extended-release opioids: where should we begin?
|
|---|---|
| Published in |
International Journal of General Medicine, December 2011
|
| DOI | 10.2147/ijgm.s24287 |
| Pubmed ID | |
| Authors |
Srinivas Nalamachu |
| Abstract |
Opioid rotation is a common and necessary clinical practice in the management of chronic non-cancer pain to improve therapeutic efficacy with the lowest opioid dose. When dose escalations fail to achieve adequate analgesia or are associated with intolerable side effects, a trial of a new opioid should be considered. Much of the scientific rationale of opioid rotation is based on the wide interindividual variability in sensitivity to opioid analgesics and the novel patient response observed when introducing an opioid-tolerant patient to a new opioid. This article discusses patient indicators for opioid rotation, the conversion process between opioid medications, and additional practical considerations for increasing the effectiveness of opioid therapy during a trial of a new opioid. A Patient vignette that demonstrates a step-wise approach to opioid rotation is also presented. |
Mendeley readers
The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 18 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 5 | 28% |
| Other | 3 | 17% |
| Lecturer | 2 | 11% |
| Student > Ph. D. Student | 2 | 11% |
| Student > Master | 1 | 6% |
| Other | 3 | 17% |
| Unknown | 2 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 13 | 72% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 11% |
| Agricultural and Biological Sciences | 1 | 6% |
| Unknown | 2 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2015.
All research outputs
#22,759,802
of 25,374,917 outputs
Outputs from International Journal of General Medicine
#1,309
of 1,653 outputs
Outputs of similar age
#225,914
of 246,219 outputs
Outputs of similar age from International Journal of General Medicine
#16
of 20 outputs
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