| Title |
Buprenorphine and pain treatment in pediatric patients: an update
|
|---|---|
| Published in |
Journal of Pain Research, March 2018
|
| DOI | 10.2147/jpr.s153903 |
| Pubmed ID | |
| Authors |
Erendira Vicencio-Rosas, María Gabriela Pérez-Guillé, Carmen Flores-Pérez, Janett Flores-Pérez, Francisca Trujillo-Jiménez, Juan Luis Chávez-Pacheco |
| Abstract |
The usual management of moderate to severe pain is based on the use of opioids. Buprenorphine (BPN) is an opioid with an analgesic potency 50 times greater than that of morphine. It is widely used in various pain models and has demonstrated efficacy and safety in adult patients; however, there are insufficient clinical trials in pediatric populations. The aim of this study was to perform an updated meta-analysis on the implementation of BPN in the treatment of pain in the pediatric population. A bibliographic search was carried out in different biomedical databases to identify scientific papers and clinical trials with evidence of BPN use in children and adolescents. A total of 89 articles were found, of which 66 were selected. Analysis of these items revealed additional sources, and the final review included a total of 112 publications. Few studies were found regarding the efficacy and safety of BPN use in children. In recent years, the use of this drug in the pediatric population has become widespread, so it is imperative to perform clinical trials and pharmacological and pharmacovigilance studies, which will allow researchers to develop dosage schemes based on the evidence and minimize the risk of adverse effects. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 59 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 14% |
| Student > Master | 7 | 12% |
| Student > Postgraduate | 6 | 10% |
| Student > Bachelor | 5 | 8% |
| Other | 5 | 8% |
| Other | 4 | 7% |
| Unknown | 24 | 41% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 11 | 19% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 12% |
| Biochemistry, Genetics and Molecular Biology | 5 | 8% |
| Nursing and Health Professions | 2 | 3% |
| Psychology | 2 | 3% |
| Other | 6 | 10% |
| Unknown | 26 | 44% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 November 2020.
All research outputs
#15,495,840
of 23,028,364 outputs
Outputs from Journal of Pain Research
#1,165
of 1,764 outputs
Outputs of similar age
#211,635
of 331,165 outputs
Outputs of similar age from Journal of Pain Research
#40
of 53 outputs
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