The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
As of 1 July 2024, you may notice a temporary increase in the numbers of X profiles with Unknown location. Click here to learn more.
| Title |
Proton pump inhibitor-refractory gastroesophageal reflux disease: challenges and solutions
|
|---|---|
| Published in |
Clinical and Experimental Gastroenterology, March 2018
|
| DOI | 10.2147/ceg.s121056 |
| Pubmed ID | |
| Authors |
Joseph Mermelstein, Alanna Chait Mermelstein, Maxwell M Chait |
| Abstract |
A significant percentage of patients with gastroesophageal reflux disease (GERD) will not respond to proton pump inhibitor (PPI) therapy. The causes of PPI-refractory GERD are numerous and diverse, and include adherence, persistent acid, functional disorders, nonacid reflux, and PPI bioavailability. The evaluation should start with a symptom assessment and may progress to imaging, endoscopy, and monitoring of esophageal pH, impedance, and bilirubin. There are a variety of pharmacologic and procedural interventions that should be selected based on the underlying mechanism of PPI failure. Pharmacologic treatments can include antacids, prokinetics, alginates, bile acid binders, reflux inhibitors, and antidepressants. Procedural options include laparoscopic fundoplication and LINX as well as endoscopic procedures, such as transoral incisionless fundoplication and Stretta. Several alternative and complementary treatments of possible benefit also exist. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 91 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 14% |
| Researcher | 11 | 12% |
| Student > Bachelor | 9 | 10% |
| Other | 6 | 7% |
| Lecturer | 5 | 5% |
| Other | 16 | 18% |
| Unknown | 31 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 29 | 32% |
| Nursing and Health Professions | 8 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 7% |
| Biochemistry, Genetics and Molecular Biology | 5 | 5% |
| Unspecified | 2 | 2% |
| Other | 6 | 7% |
| Unknown | 35 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2021.
All research outputs
#3,236,251
of 23,033,713 outputs
Outputs from Clinical and Experimental Gastroenterology
#54
of 307 outputs
Outputs of similar age
#68,629
of 331,165 outputs
Outputs of similar age from Clinical and Experimental Gastroenterology
#3
of 6 outputs
Altmetric has tracked 23,033,713 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 307 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.7. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,165 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.