Title |
Nano-selenium and its nanomedicine applications: a critical review
|
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Published in |
International Journal of Nanomedicine, April 2018
|
DOI | 10.2147/ijn.s157541 |
Pubmed ID | |
Authors |
Bozena Hosnedlova, Marta Kepinska, Sylvie Skalickova, Carlos Fernandez, Branislav Ruttkay-Nedecky, Qiuming Peng, Mojmir Baron, Magdalena Melcova, Radka Opatrilova, Jarmila Zidkova, Geir Bjørklund, Jiri Sochor, Rene Kizek |
Abstract |
Traditional supplements of selenium generally have a low degree of absorption and increased toxicity. Therefore, it is imperative to develop innovative systems as transporters of selenium compounds, which would raise the bioavailability of this element and allow its controlled release in the organism. Nanoscale selenium has attracted a great interest as a food additive especially in individuals with selenium deficiency, but also as a therapeutic agent without significant side effects in medicine. This review is focused on the incorporation of nanotechnological applications, in particular exploring the possibilities of a more effective way of administration, especially in selenium-deficient organisms. In addition, this review summarizes the survey of knowledge on selenium nanoparticles, their biological effects in the organism, advantages, absorption mechanisms, and nanotechnological applications for peroral administration. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Norway | 1 | 20% |
Canada | 1 | 20% |
Unknown | 3 | 60% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 461 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Unspecified | 71 | 15% |
Student > Ph. D. Student | 62 | 13% |
Student > Master | 46 | 10% |
Student > Bachelor | 37 | 8% |
Researcher | 29 | 6% |
Other | 83 | 18% |
Unknown | 133 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Unspecified | 71 | 15% |
Biochemistry, Genetics and Molecular Biology | 61 | 13% |
Agricultural and Biological Sciences | 38 | 8% |
Chemistry | 37 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 17 | 4% |
Other | 84 | 18% |
Unknown | 153 | 33% |