↓ Skip to main content

Dove Medical Press

Article Metrics

The link between chronic obstructive pulmonary disease phenotypes and histological subtypes of lung cancer: a case–control study

Overview of attention for article published in International Journal of Chronic Obstructive Pulmonary Disease, April 2018
Altmetric Badge

Mentioned by

twitter
1 tweeter

Citations

dimensions_citation
6 Dimensions

Readers on

mendeley
17 Mendeley
Title
The link between chronic obstructive pulmonary disease phenotypes and histological subtypes of lung cancer: a case–control study
Published in
International Journal of Chronic Obstructive Pulmonary Disease, April 2018
DOI 10.2147/copd.s158818
Pubmed ID
Authors

Wei Wang, Mengshuang Xie, Shuang Dou, Liwei Cui, Chunyan Zheng, Wei Xiao

Abstract

COPD is considered an independent risk factor for lung cancer. COPD and lung cancer are both very heterogeneous diseases, and the study herein investigates the link between COPD phenotypes and specific histological subtypes of lung cancer. This case-control study comprised 2,283 patients with newly diagnosed pathological lung cancer and 2,323 non-lung cancer controls. All participants underwent pulmonary function tests. The diagnosis of COPD was based on Global Initiative for Chronic Obstructive Lung Disease criteria. Subtypes of the two diseases were categorized according to 2015 World Health Organization classification of lung cancer and computer quantification of airway collapse on maximum expiratory flow volume. ORs were estimated using logistic regression analysis. The prevalence of COPD was higher (32.8%) in lung cancer patients compared to controls (16.0%). After adjustment for age, sex, body-mass index, and smoking status, the presence of COPD significantly increased the risk of lung cancer (OR 2.88, 95% CI 2.48-3.34) and all common histological subtypes (ORs 2.04-5.26). Both emphysema-predominant and non-emphysema-predominant phenotypes of COPD significantly increased the risk of lung cancer (OR 4.43, 95% CI 2.85-6.88; OR 2.82, 95% CI 2.40-3.31). Higher risk of squamous-cell carcinoma and small-cell lung cancer was observed in patients with the emphysema-predominant than the non-emphysema-predominant phenotype (OR 1.73, 95% CI 1.03-2.89; OR 3.74, 95% CI 1.64-8.53). COPD was an independent risk factor for lung cancer and all common histological subtypes. Both emphysema-predominant and non-emphysema-predominant phenotypes of COPD significantly increased the risk of lung cancer. Relative to non-emphysema-predominant phenotype of COPD, emphysema-predominant phenotype had a higher risk of squamous-cell carcinoma and small-cell lung cancer.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 24%
Student > Master 4 24%
Student > Ph. D. Student 3 18%
Student > Doctoral Student 1 6%
Other 1 6%
Other 1 6%
Unknown 3 18%
Readers by discipline Count As %
Medicine and Dentistry 6 35%
Biochemistry, Genetics and Molecular Biology 2 12%
Computer Science 1 6%
Agricultural and Biological Sciences 1 6%
Immunology and Microbiology 1 6%
Other 3 18%
Unknown 3 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 April 2018.
All research outputs
#10,222,385
of 12,801,247 outputs
Outputs from International Journal of Chronic Obstructive Pulmonary Disease
#1,253
of 1,563 outputs
Outputs of similar age
#204,999
of 271,792 outputs
Outputs of similar age from International Journal of Chronic Obstructive Pulmonary Disease
#53
of 58 outputs
Altmetric has tracked 12,801,247 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,563 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one is in the 6th percentile – i.e., 6% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 271,792 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.