| Title |
Severe mental illness and chronic kidney disease: a cross-sectional study in the United Kingdom
|
|---|---|
| Published in |
Clinical Epidemiology, April 2018
|
| DOI | 10.2147/clep.s154841 |
| Pubmed ID | |
| Authors |
Masao Iwagami, Kathryn E Mansfield, Joseph F Hayes, Kate Walters, David PJ Osborn, Liam Smeeth, Dorothea Nitsch, Laurie A Tomlinson |
| Abstract |
We investigated the burden of chronic kidney disease (CKD) among patients with severe mental illness (SMI). We identified patients with SMI among all those aged 25-74 registered in the UK Clinical Practice Research Datalink as on March 31, 2014. We compared the prevalence of CKD (two measurements of estimated glomerular filtration rate <60 mL/min/1.73 m2 for ≥3 months) and renal replacement therapy between patients with and without SMI. For patients with and without a history of lithium prescription separately, we used logistic regression to examine the association between SMI and CKD, adjusting for demographics, lifestyle characteristics, and known CKD risk factors. The CKD prevalence was 14.6% among patients with SMI and a history of lithium prescription (n = 4,295), 3.3% among patients with SMI and no history of lithium prescription (n = 24,101), and 2.1% among patients without SMI (n = 2,387,988; P < 0.001). The prevalence of renal replacement therapy was 0.23%, 0.15%, and 0.11%, respectively (P = 0.012). Compared to patients without SMI, the fully adjusted odds ratio for CKD was 6.49 (95% CI 5.84-7.21) for patients with SMI and a history of lithium prescription and 1.45 (95% CI 1.34-1.58) for patients with SMI and no history of lithium prescription. The higher prevalence of CKD in patients with SMI may, in part, be explained by more frequent blood testing as compared to the general population. CKD is identified more commonly among patients with SMI than in the general population. |
X Demographics
The data shown below were collected from the profiles of 33 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 18 | 55% |
| United States | 2 | 6% |
| Chile | 1 | 3% |
| Sweden | 1 | 3% |
| Unknown | 11 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 21 | 64% |
| Practitioners (doctors, other healthcare professionals) | 8 | 24% |
| Scientists | 2 | 6% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
| Unknown | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 75 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 15 | 20% |
| Student > Ph. D. Student | 12 | 16% |
| Student > Bachelor | 10 | 13% |
| Student > Master | 9 | 12% |
| Other | 4 | 5% |
| Other | 8 | 11% |
| Unknown | 17 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 20 | 27% |
| Nursing and Health Professions | 7 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
| Biochemistry, Genetics and Molecular Biology | 3 | 4% |
| Psychology | 3 | 4% |
| Other | 13 | 17% |
| Unknown | 25 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 27. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 November 2022.
All research outputs
#1,465,964
of 25,654,806 outputs
Outputs from Clinical Epidemiology
#62
of 798 outputs
Outputs of similar age
#31,645
of 344,586 outputs
Outputs of similar age from Clinical Epidemiology
#4
of 29 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 798 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.6. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,586 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.