| Title |
Cattle encephalon glycoside and ignotin injection improves cognitive impairment in APPswe/PS1dE9 mice used as multitarget anti-Alzheimer’s drug candidates
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, February 2015
|
| DOI | 10.2147/ndt.s78025 |
| Pubmed ID | |
| Authors |
Ya Gao, Ya-zhuo Hu, Rui-sheng Li, Zhi-tao Han, Yan Geng, Zheng Xia, Wen-jin Du, Li-xin Liu, Hong-hong Zhang, Lu-ning Wang |
| Abstract |
Cattle encephalon glycoside and ignotin injection (CEGI), a multitargeted neurotrophic drug, has been widely used in the treatment of central and peripheral nerve injuries, such as stroke, hypoxic ischemic encephalopathy, and diabetic neuropathy in the People's Republic of China. However, data regarding the effect of CEGI on Alzheimer's disease (AD) remain scarce. The present study aimed to investigate the effect of CEGI on learning and memory in an APPswe/PS1dE9 double-transgenic mouse model, a suitable animal model of AD, and elucidate its possible mechanisms. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 31 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 9 | 29% |
| Student > Ph. D. Student | 5 | 16% |
| Researcher | 4 | 13% |
| Unspecified | 3 | 10% |
| Student > Doctoral Student | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 8 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 5 | 16% |
| Neuroscience | 4 | 13% |
| Unspecified | 3 | 10% |
| Sports and Recreations | 3 | 10% |
| Medicine and Dentistry | 2 | 6% |
| Other | 5 | 16% |
| Unknown | 9 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2015.
All research outputs
#3,710,309
of 25,374,647 outputs
Outputs from Neuropsychiatric Disease and Treatment
#553
of 3,132 outputs
Outputs of similar age
#51,133
of 361,169 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#18
of 58 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,132 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 361,169 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.