| Title |
Stimulation of proinflammatory cytokines by volatile sulfur compounds in endodontically treated teeth
|
|---|---|
| Published in |
International Journal of General Medicine, March 2015
|
| DOI | 10.2147/ijgm.s77693 |
| Pubmed ID | |
| Authors |
Johann Lechner, Volker von Baehr |
| Abstract |
Persistent microorganisms in endodontically treated teeth produce volatile sulfur compounds (VSC) such as methyl mercaptan, hydrogen sulfide, and thioether. In this retrospective study, we evaluated the ex vivo immune response of peripheral blood mononuclear cells to sulfur compounds in 354 patients with systemic diseases. These systemic findings are correlated with semiquantitative values of a VSC indicator applied directly on endodontically treated teeth. Data elucidate the role of VSC in patients with immunologic diseases and the role of a semiquantitative chairside test, like the VSC indicator presented here, in correlation to IFNg and IL-10 sensitization in peripheral blood mononuclear cells. The association between ex vivo-stimulated cytokines and endodontically derived sulfur components is supported by the fact that the number of interferon gamma- and/or interleukin-10-positive sensitized patients declined significantly 3-8 months after extraction of the corresponding teeth. |
Mendeley readers
The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 12 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 2 | 17% |
| Student > Doctoral Student | 1 | 8% |
| Other | 1 | 8% |
| Student > Master | 1 | 8% |
| Student > Postgraduate | 1 | 8% |
| Other | 0 | 0% |
| Unknown | 6 | 50% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 4 | 33% |
| Nursing and Health Professions | 1 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 8% |
| Unknown | 6 | 50% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 July 2021.
All research outputs
#18,403,994
of 22,796,179 outputs
Outputs from International Journal of General Medicine
#947
of 1,445 outputs
Outputs of similar age
#186,542
of 256,542 outputs
Outputs of similar age from International Journal of General Medicine
#5
of 7 outputs
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So far Altmetric has tracked 1,445 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.7. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
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