Title |
Budget impact model for oncopharmacogenetics from the perspective of mandatory basic health insurance in Switzerland using the example of breast cancer
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Published in |
Pharmacogenomics and Personalized Medicine, April 2018
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DOI | 10.2147/pgpm.s154368 |
Pubmed ID | |
Authors |
Thomas D Szucs, Kevin P Szillat, Eva Blozik |
Abstract |
Single-nucleotide polymorphisms (SNPs) can severely impact individual drug response and health outcomes in cancer patients. Genetic tests to screen for marker SNPs are available to adjust the drug dose of oncologicals to the patient's needs. However, it is unclear whether the positive effects outbalance the increased costs or even lead to an overall cost reduction. This very pragmatic analysis used three frequently used oncologicals for the treatment of breast cancer to evaluate whether preemptive pharmacogenetic testing may have a cost-reducing impact on health care spending in the Swiss health care system. Our results indicate that oncopharmacogenetics might help to reduce health care costs (ie, by avoiding adverse drug effects) and to increase efficiency of drugs in oncologic patients. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 27 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 22% |
Other | 2 | 7% |
Unspecified | 2 | 7% |
Student > Master | 2 | 7% |
Student > Doctoral Student | 2 | 7% |
Other | 8 | 30% |
Unknown | 5 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Economics, Econometrics and Finance | 5 | 19% |
Biochemistry, Genetics and Molecular Biology | 4 | 15% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 11% |
Nursing and Health Professions | 2 | 7% |
Unspecified | 2 | 7% |
Other | 5 | 19% |
Unknown | 6 | 22% |