Title |
Detection of cytomegalovirus in an immunocompetent adult presenting with acute retinal necrosis due to varicella-zoster virus: a case report
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Published in |
Clinical Ophthalmology, May 2015
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DOI | 10.2147/opth.s81020 |
Pubmed ID | |
Authors |
Tomoko Nakamura, Tohru Daikoku, Kimiyasu Shiraki, Atsushi Hayashi |
Abstract |
To report a case of simultaneous detection of cytomegalovirus (CMV) in acute retinal necrosis (ARN) due to varicella-zoster virus (VZV) in an immunocompetent adult. A 65-year-old healthy woman presented with necrotizing retinitis. Vitreous, tears, saliva, and swabs of the auricular and forehead skin areas were collected and tested by polymerase chain reaction analysis at various time points during the treatment period. VZV and CMV DNA were detected in the vitreous, tears, saliva, and skin. CMV was present in fewer copies than VZV in the vitreous. The retinal lesion clinically improved rapidly only by acyclovir. According to the clinical findings and the clinical responses to acyclovir, CMV seems not to cause ARN in this case. VZV and CMV DNA were detected in the vitreous of a patient with VZV ARN. CMV reactivation appeared to be asymptomatic. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Postgraduate | 3 | 17% |
Student > Master | 3 | 17% |
Other | 2 | 11% |
Student > Bachelor | 1 | 6% |
Lecturer | 1 | 6% |
Other | 2 | 11% |
Unknown | 6 | 33% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 10 | 56% |
Biochemistry, Genetics and Molecular Biology | 1 | 6% |
Unknown | 7 | 39% |