| Title |
Different presence of Chlamydia pneumoniae, herpes simplex virus type 1, human herpes virus 6, and Toxoplasma gondii in schizophrenia: meta-analysis and analytical study
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, March 2015
|
| DOI | 10.2147/ndt.s79285 |
| Pubmed ID | |
| Authors |
José Gutiérrez-Fernández, Juan de Dios Luna del Castillo, Sara Mañanes-González, José Antonio Carrillo-Ávila, Blanca Gutiérrez, Jorge A Cervilla, Antonio Sorlózano-Puerto |
| Abstract |
In the present study we have performed both a meta-analysis and an analytical study exploring the presence of Chlamydia pneumoniae, herpes simplex virus type 1, human herpes virus 6, and Toxoplasma gondii antibodies in a sample of 143 schizophrenic patients and 143 control subjects. The meta-analysis was performed on papers published up to April 2014. The presence of serum immunoglobulin G and immunoglobulin A was performed by enzyme-linked immunosorbent assay test. The detection of microbial DNA in total peripheral blood was performed by nested polymerase chain reaction. The meta-analysis showed that: 1) C. pneumoniae DNA in blood and brain are more common in schizophrenic patients; 2) there is association with parasitism by T. gondii, despite the existence of publication bias; and 3) herpes viruses were not more common in schizophrenic patients. In our sample only anti-Toxoplasma immunoglobulin G was more prevalent and may be a risk factor related to schizophrenia, with potential value for prevention. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 1% |
| Unknown | 66 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 12% |
| Student > Master | 8 | 12% |
| Student > Bachelor | 7 | 10% |
| Student > Ph. D. Student | 6 | 9% |
| Other | 6 | 9% |
| Other | 17 | 25% |
| Unknown | 15 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 18 | 27% |
| Agricultural and Biological Sciences | 12 | 18% |
| Neuroscience | 4 | 6% |
| Immunology and Microbiology | 4 | 6% |
| Nursing and Health Professions | 1 | 1% |
| Other | 6 | 9% |
| Unknown | 22 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 April 2015.
All research outputs
#19,944,994
of 25,374,647 outputs
Outputs from Neuropsychiatric Disease and Treatment
#2,192
of 3,132 outputs
Outputs of similar age
#187,271
of 270,992 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#47
of 69 outputs
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