| Title |
Study of antitumor activity in breast cell lines using silver nanoparticles produced by yeast
|
|---|---|
| Published in |
International Journal of Nanomedicine, March 2015
|
| DOI | 10.2147/ijn.s75835 |
| Pubmed ID | |
| Authors |
Francisco G Ortega, Martín A Fernández-Baldo, Jorge G Fernández, María J Serrano, María I Sanz, Juan J Diaz-Mochón, José A Lorente, Julio Raba |
| Abstract |
In the present article, we describe a study of antitumor activity in breast cell lines using silver nanoparticles (Ag NPs) synthesized by a microbiological method. These Ag NPs were tested for their antitumor activity against MCF7 and T47D cancer cells and MCF10-A normal breast cell line. We analyzed cell viability, apoptosis induction, and endocytosis activity of those cell lines and we observed that the effects of the biosynthesized Ag NPs were directly related with the endocytosis activity. Moreover, Ag NPs had higher inhibition efficacy in tumor lines than in normal lines of breast cells, which is due to the higher endocytic activity of tumor cells compared to normal cells. In this way, we demonstrate that biosynthesized Ag NPs can be an alternative for the treatment of tumors. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 88 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 19 | 22% |
| Student > Ph. D. Student | 13 | 15% |
| Researcher | 8 | 9% |
| Student > Bachelor | 7 | 8% |
| Professor | 5 | 6% |
| Other | 14 | 16% |
| Unknown | 22 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 15 | 17% |
| Chemistry | 9 | 10% |
| Medicine and Dentistry | 7 | 8% |
| Biochemistry, Genetics and Molecular Biology | 6 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 6% |
| Other | 15 | 17% |
| Unknown | 31 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 April 2015.
All research outputs
#22,756,649
of 25,371,288 outputs
Outputs from International Journal of Nanomedicine
#3,598
of 4,121 outputs
Outputs of similar age
#232,494
of 271,001 outputs
Outputs of similar age from International Journal of Nanomedicine
#63
of 77 outputs
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We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.