Title |
Management of neovascular age-related macular degeneration: current state-of-the-art care for optimizing visual outcomes and therapies in development
|
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Published in |
Clinical Ophthalmology, June 2015
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DOI | 10.2147/opth.s74959 |
Pubmed ID | |
Authors |
Aniruddha Agarwal, William R Rhoades, Mostafa Hanout, Mohamed Kamel Soliman, Salman Sarwar, Mohammad Ali Sadiq, Yasir Jamal Sepah, Diana V, Quan Dong Nguyen |
Abstract |
Contemporary management of neovascular age-related macular degeneration (AMD) has evolved significantly over the last few years. The goal of treatment is shifting from merely salvaging vision to maintaining a high quality of life. There have been significant breakthroughs in the identification of viable drug targets and gene therapies. Imaging tools with near-histological precision have enhanced our knowledge about pathophysiological mechanisms that play a role in vision loss due to AMD. Visual, social, and vocational rehabilitation are all important treatment goals. In this review, evidence from landmark clinical trials is summarized to elucidate the optimum modern-day management of neovascular AMD. Therapeutic strategies currently under development, such as gene therapy and personalized medicine, are also described. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 100 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 16 | 16% |
Student > Master | 15 | 15% |
Student > Bachelor | 11 | 11% |
Other | 11 | 11% |
Student > Ph. D. Student | 9 | 9% |
Other | 12 | 12% |
Unknown | 26 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 32 | 32% |
Agricultural and Biological Sciences | 8 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 6% |
Nursing and Health Professions | 4 | 4% |
Biochemistry, Genetics and Molecular Biology | 4 | 4% |
Other | 17 | 17% |
Unknown | 29 | 29% |