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IncobotulinumtoxinA in aesthetics: Russian multidisciplinary expert consensus recommendations

Overview of attention for article published in Clinical, Cosmetic and Investigational Dermatology, June 2015
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Title
IncobotulinumtoxinA in aesthetics: Russian multidisciplinary expert consensus recommendations
Published in
Clinical, Cosmetic and Investigational Dermatology, June 2015
DOI 10.2147/ccid.s72301
Pubmed ID
Authors

Gill Hughes, Elena Gubanova, Irina Khrustaleva, Vasiliy Atamanov, Anastasiya Saybel, Elena Parsagashvili, Irina  Dmitrieva, Elena Sanchez, Natalia Lapatina, Tatiana Korolkova, Alena Saromytskaya, Elena Goltsova, Elmira Satardinova, Yana Yutskovskaya

Abstract

Although there are various international consensus recommendations on the use of botulinum neurotoxin type A (BoNT/A) in facial aesthetics, there are no global or Russian guidelines on the optimal dose of incobotulinumtoxinA, free from complexing proteins, within specific aesthetic indications. This article reports the outcomes of two expert consensus meetings, conducted to review and analyze efficacy and tolerability data for incobotulinumtoxinA in various facial aesthetic indications and to give expert consensus recommendations to ensure best clinical practice among Russian clinicians. Thirteen dermatology and/or plastic surgery experts attended meetings held in Paris, France (November 2013), and Moscow, Russia (March 2014). The expert group reviewed and analyzed the existing evidence, consensus recommendations, and Russian experts' extensive practical experience of incobotulinumtoxinA in aesthetics to reach consensus on optimal doses, potential dose adjustments, and injection sites of incobotulinumtoxinA for facial aesthetics. All experts developed guidance on the optimal doses for incobotulinumtoxinA treatment of different regions of the upper and lower face. The expert panel agreed that there are no differences in the efficacy and duration of the effect between the four BoNT/As that are commercially available for facial aesthetic indications in Russia and that, when administered correctly, all BoNT/As can achieve optimal results. Experts also agreed that nonresponse to BoNT/A can be caused by neutralizing antibodies. On the basis of the scientific and clinical evidence available for incobotulinumtoxinA, coupled with the extensive clinical experience of the consensus group, experts recommended the optimal doses of incobotulinumtoxinA effective for treatment of wrinkles of the upper and lower face to achieve the expected aesthetic outcome. These first Russian guidelines on the optimal use of incobotulinumtoxinA for augmentation of glabellar lines, periorbital wrinkles, forehead lines, bunny lines, perioral wrinkles, depressor anguli oris, mentalis, masseters and platysmal bands, and performing the Nefertiti lift, are presented here.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 3 18%
Student > Master 3 18%
Student > Postgraduate 2 12%
Other 2 12%
Lecturer 2 12%
Other 5 29%
Readers by discipline Count As %
Medicine and Dentistry 11 65%
Agricultural and Biological Sciences 2 12%
Nursing and Health Professions 2 12%
Psychology 1 6%
Unspecified 1 6%
Other 0 0%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 June 2015.
All research outputs
#2,586,848
of 5,222,019 outputs
Outputs from Clinical, Cosmetic and Investigational Dermatology
#79
of 157 outputs
Outputs of similar age
#90,220
of 176,430 outputs
Outputs of similar age from Clinical, Cosmetic and Investigational Dermatology
#7
of 16 outputs
Altmetric has tracked 5,222,019 research outputs across all sources so far. This one is in the 47th percentile – i.e., 47% of other outputs scored the same or lower than it.
So far Altmetric has tracked 157 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 176,430 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.