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| Title |
A review of vagus nerve stimulation as a therapeutic intervention
|
|---|---|
| Published in |
Journal of Inflammation Research, May 2018
|
| DOI | 10.2147/jir.s163248 |
| Pubmed ID | |
| Authors |
Rhaya L Johnson, Christopher G Wilson |
| Abstract |
In this review, we provide an overview of the US Food and Drug Administration (FDA)-approved clinical uses of vagus nerve stimulation (VNS) as well as information about the ongoing studies and preclinical research to expand the use of VNS to additional applications. VNS is currently FDA approved for therapeutic use in patients aged >12 years with drug-resistant epilepsy and depression. Recent studies of VNS in in vivo systems have shown that it has anti-inflammatory properties which has led to more preclinical research aimed at expanding VNS treatment across a wider range of inflammatory disorders. Although the signaling pathway and mechanism by which VNS affects inflammation remain unknown, VNS has shown promising results in treating chronic inflammatory disorders such as sepsis, lung injury, rheumatoid arthritis (RA), and diabetes. It is also being used to control pain in fibromyalgia and migraines. This new preclinical research shows that VNS bears the promise of being applied to a wider range of therapeutic applications. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 33% |
| Canada | 1 | 7% |
| Curaçao | 1 | 7% |
| Germany | 1 | 7% |
| Unknown | 7 | 47% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 53% |
| Scientists | 4 | 27% |
| Practitioners (doctors, other healthcare professionals) | 3 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 744 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 744 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 101 | 14% |
| Student > Master | 81 | 11% |
| Researcher | 78 | 10% |
| Student > Bachelor | 74 | 10% |
| Other | 36 | 5% |
| Other | 114 | 15% |
| Unknown | 260 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 122 | 16% |
| Neuroscience | 90 | 12% |
| Engineering | 78 | 10% |
| Psychology | 29 | 4% |
| Biochemistry, Genetics and Molecular Biology | 28 | 4% |
| Other | 118 | 16% |
| Unknown | 279 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 188. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2024.
All research outputs
#215,744
of 25,837,817 outputs
Outputs from Journal of Inflammation Research
#10
of 982 outputs
Outputs of similar age
#4,833
of 341,925 outputs
Outputs of similar age from Journal of Inflammation Research
#1
of 10 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 982 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.3. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,925 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them