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Pulmonary hemodynamic profile in chronic obstructive pulmonary disease

Overview of attention for article published in International Journal of Chronic Obstructive Pulmonary Disease, July 2015
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Mentioned by

twitter
3 tweeters

Citations

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34 Dimensions

Readers on

mendeley
29 Mendeley
Title
Pulmonary hemodynamic profile in chronic obstructive pulmonary disease
Published in
International Journal of Chronic Obstructive Pulmonary Disease, July 2015
DOI 10.2147/copd.s78180
Pubmed ID
Authors

Karina Portillo, Yolanda Torralba, Isabel Blanco, Felip Burgos, Roberto Rodriguez -Roisin, Jose Rios, Josep Roca, Joan Albert Barberà

Abstract

Few data are available in regards to the prevalence of pulmonary hypertension (PH) in the broad spectrum of COPD. This study was aimed at assessing the prevalence of PH in a cohort of COPD patients across the severity of airflow limitation, and reporting the hemodynamic characteristics at rest and during exercise. We performed a retrospective analysis on COPD patients who underwent right-heart catheterization in our center with measurements obtained at rest (n=139) and during exercise (n=85). PH was defined as mean pulmonary artery pressure (mPAP) ≥25 mmHg and pulmonary capillary wedge pressure <15 mmHg. Exercise-induced PH (EIPH) was defined by a ratio of ΔmPAP/Δcardiac output >3. PH was present in 25 patients (18%). According to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) classification, PH prevalence in GOLD 2 was 7% (3 patients); 25% (14 patients) in GOLD 3; and 22% (8 patients) in GOLD 4. Severe PH (mPAP ≥35 mmHg) was identified in four patients (2.8%). Arterial partial oxygen pressure was the outcome most strongly associated with PH (r=-0.29, P<0.001). EIPH was observed in 60 patients (71%) and had a similar prevalence in both GOLD 2 and 3, and was present in all GOLD 4 patients. Patients with PH had lower cardiac index during exercise than patients without PH (5.0±1.2 versus 6.7±1.4 L/min/m(2), respectively; P=0.001). PH has a similar prevalence in COPD patients with severe and very-severe airflow limitation, being associated with the presence of arterial hypoxemia. In contrast, EIPH is highly prevalent, even in moderate COPD, and might contribute to limiting exercise tolerance.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
India 1 3%
Unknown 27 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 34%
Student > Postgraduate 3 10%
Professor > Associate Professor 3 10%
Student > Master 2 7%
Professor 1 3%
Other 3 10%
Unknown 7 24%
Readers by discipline Count As %
Medicine and Dentistry 14 48%
Nursing and Health Professions 2 7%
Mathematics 1 3%
Computer Science 1 3%
Sports and Recreations 1 3%
Other 1 3%
Unknown 9 31%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 July 2015.
All research outputs
#2,865,106
of 5,395,569 outputs
Outputs from International Journal of Chronic Obstructive Pulmonary Disease
#359
of 685 outputs
Outputs of similar age
#102,501
of 186,416 outputs
Outputs of similar age from International Journal of Chronic Obstructive Pulmonary Disease
#39
of 83 outputs
Altmetric has tracked 5,395,569 research outputs across all sources so far. This one is in the 33rd percentile – i.e., 33% of other outputs scored the same or lower than it.
So far Altmetric has tracked 685 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 186,416 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 83 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.