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Effect of liposomal fluidity on skin permeation of sodium fluorescein entrapped in liposomes

Overview of attention for article published in International Journal of Nanomedicine, July 2015
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Mentioned by

twitter
3 tweeters

Citations

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14 Dimensions

Readers on

mendeley
20 Mendeley
Title
Effect of liposomal fluidity on skin permeation of sodium fluorescein entrapped in liposomes
Published in
International Journal of Nanomedicine, July 2015
DOI 10.2147/ijn.s86624
Pubmed ID
Authors

Tanasait Ngawhirunpat, Thirapit Subongkot

Abstract

The purpose of this study was to investigate the effect of ultradeformable liposome components, Tween 20 and terpenes, on vesicle fluidity. The fluidity was evaluated by electron spin resonance spectroscopy using 5-doxyl stearic acid and 16-doxyl stearic acid as spin labels for phospholipid bilayer fluidity at the C5 atom of the acyl chain near the polar head group (hydrophilic region) and the C16 atom of the acyl chain (lipophilic region), respectively. The electron spin resonance study revealed that Tween 20 increased the fluidity at the C5 atom of the acyl chain, whereas terpenes increased the fluidity at the C16 atom of the acyl chain of the phospholipid bilayer. The increase in liposomal fluidity resulted in the increased skin penetration of sodium fluorescein. Confocal laser scanning microscopy showed that ultradeformable liposomes with terpenes increase the skin penetration of sodium fluorescein by enhancing hair follicle penetration.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Pakistan 1 5%
Unknown 19 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 35%
Student > Master 4 20%
Professor 3 15%
Researcher 2 10%
Student > Bachelor 1 5%
Other 1 5%
Unknown 2 10%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 5 25%
Agricultural and Biological Sciences 3 15%
Chemistry 3 15%
Medicine and Dentistry 3 15%
Physics and Astronomy 2 10%
Other 1 5%
Unknown 3 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 July 2015.
All research outputs
#2,668,282
of 5,376,712 outputs
Outputs from International Journal of Nanomedicine
#526
of 1,436 outputs
Outputs of similar age
#93,897
of 188,199 outputs
Outputs of similar age from International Journal of Nanomedicine
#63
of 140 outputs
Altmetric has tracked 5,376,712 research outputs across all sources so far. This one is in the 47th percentile – i.e., 47% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,436 research outputs from this source. They receive a mean Attention Score of 1.8. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 188,199 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 140 others from the same source and published within six weeks on either side of this one. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.