| Title |
Properties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination
|
|---|---|
| Published in |
International Journal of Nanomedicine, May 2018
|
| DOI | 10.2147/ijn.s154743 |
| Pubmed ID | |
| Authors |
Lei Zhang, Wendi Yang, Chaohua Hu, Qianchao Wang, Yunkun Wu |
| Abstract |
Vaccination is one of the most effective approaches in the prevention and control of disease worldwide. Oral vaccination could have wide applications if effective protection cannot be achieved through traditional (eg, parenteral) routes of vaccination. However, oral administration is hampered by the difficulties in transferring vaccines in vivo. This has led to the development of materials such as carriers with potential adjuvant effects. Considering the requirements for selecting adjuvants for oral vaccines as well as the advantages of nanoparticle/microparticle materials as immune effectors and antigen conveyors, synthetic materials could improve the efficiency of oral vaccination. In this review, nanoparticles and microparticles with adjuvant characteristics are described with regard to their potential importance for oral immunization, and some promising and successful modification strategies are summarized. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 48 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 10 | 21% |
| Student > Ph. D. Student | 7 | 15% |
| Student > Bachelor | 3 | 6% |
| Student > Doctoral Student | 2 | 4% |
| Researcher | 2 | 4% |
| Other | 7 | 15% |
| Unknown | 17 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 19% |
| Immunology and Microbiology | 4 | 8% |
| Biochemistry, Genetics and Molecular Biology | 3 | 6% |
| Social Sciences | 3 | 6% |
| Agricultural and Biological Sciences | 2 | 4% |
| Other | 6 | 13% |
| Unknown | 21 | 44% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 May 2018.
All research outputs
#17,292,294
of 25,382,440 outputs
Outputs from International Journal of Nanomedicine
#2,469
of 4,122 outputs
Outputs of similar age
#219,253
of 339,234 outputs
Outputs of similar age from International Journal of Nanomedicine
#45
of 70 outputs
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