Title |
Everolimus-eluting stent platforms in percutaneous coronary intervention: comparative effectiveness and outcomes
|
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Published in |
Medical Devices : Evidence and Research, July 2015
|
DOI | 10.2147/mder.s66360 |
Pubmed ID | |
Authors |
Vasileios F Panoulas, Ioannis Mastoris, Klio Konstantinou, Maurizio Tespili, Alfonso Ielasi |
Abstract |
Despite the remarkable benefits obtained following the introduction of the first-generation drug-eluting stent (DES), concerns were raised over its long-term safety, particularly with regard to very late (beyond 1 year) stent thrombosis. Newer-generation DESs have been developed to overcome this limitation using novel stent platforms, new drugs, more biocompatible durable polymers, and bioabsorbable polymers or backbones. To date, new-generation DESs have virtually replaced the use of first-generation DESs worldwide. In this review article, we discuss in detail the design, pharmacology, and mechanism of action of the newer-generation permanent and bioresorbable everolimus-eluting platforms. Furthermore, we present and evaluate the current evidence on the performance and safety of these devices compared to those of other available stent platforms. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 3% |
Unknown | 36 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 4 | 11% |
Student > Postgraduate | 4 | 11% |
Student > Bachelor | 4 | 11% |
Researcher | 4 | 11% |
Student > Ph. D. Student | 3 | 8% |
Other | 7 | 19% |
Unknown | 11 | 30% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 30% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 8% |
Biochemistry, Genetics and Molecular Biology | 2 | 5% |
Unspecified | 2 | 5% |
Agricultural and Biological Sciences | 1 | 3% |
Other | 3 | 8% |
Unknown | 15 | 41% |