Title |
Cardiovascular effects of hormone therapy for prostate cancer
|
---|---|
Published in |
Drug, Healthcare and Patient Safety, July 2015
|
DOI | 10.2147/dhps.s50549 |
Pubmed ID | |
Authors |
Jason F Lester, Malcolm D Mason |
Abstract |
Androgen deprivation therapy (ADT) has been the mainstay of treatment for advanced prostate cancer for decades, and has been shown to control disease and improve symptoms. In addition, for men with high-risk localized or locally advanced prostate cancer, short-course ADT in combination with radiotherapy improves survival. There is evidence that ADT increases cardiovascular risk, particularly in men with preexisting cardiovascular disease. This increased risk may apply even with short-course ADT. In an individual patient, the benefits of ADT should be balanced against the risk, and patients who require ADT should have risk factors for cardiovascular disease optimized. There is some evidence to suggest that more contemporary methods of delivering ADT may reduce cardiovascular risk. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 67% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 63 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 9 | 14% |
Student > Doctoral Student | 8 | 13% |
Student > Ph. D. Student | 7 | 11% |
Student > Master | 6 | 10% |
Professor | 5 | 8% |
Other | 17 | 27% |
Unknown | 11 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 26 | 41% |
Biochemistry, Genetics and Molecular Biology | 5 | 8% |
Nursing and Health Professions | 3 | 5% |
Agricultural and Biological Sciences | 2 | 3% |
Social Sciences | 2 | 3% |
Other | 8 | 13% |
Unknown | 17 | 27% |