Title |
Radial fundus autofluorescence in the periphery in patients with X-linked retinitis pigmentosa
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Published in |
Clinical Ophthalmology, August 2015
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DOI | 10.2147/opth.s89371 |
Pubmed ID | |
Authors |
Ken Ogino, Maho Oishi, Akio Oishi, Satoshi Morooka, Masako Sugahara, Norimoto Gotoh, Masafumi Kurimoto, Nagahisa Yoshimura |
Abstract |
To describe the peripheral autofluorescence images and clinical features of patients with retinal dystrophy who showed radial fundus autofluorescence (FAF) at the posterior pole. The authors retrospectively reviewed pooled wide-field FAF images of 711 patients with retinal dystrophy and 56 family members. Eleven eyes of seven women exhibited radial FAF at the posterior pole. Wide-field FAF showed extension of the radial pattern to the periphery in all eyes except one. One woman showed radial hyper-FAF only in the periphery, not at the posterior pole. These eight individuals were X-linked retinitis pigmentosa patients or carriers. The tapetal-like reflex was not observed in their color fundus photographs. The peripheral visual field showed wedge-shaped restriction in some individuals. Wide-field FAF imaging can depict radial FAF not only at the posterior pole but also in the periphery in X-linked retinitis pigmentosa carriers. The authors therefore agree with previous reports that radial FAF may be a hallmark of X-linked retinitis pigmentosa. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 21 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 4 | 19% |
Other | 3 | 14% |
Student > Master | 3 | 14% |
Lecturer | 1 | 5% |
Professor | 1 | 5% |
Other | 3 | 14% |
Unknown | 6 | 29% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 8 | 38% |
Agricultural and Biological Sciences | 2 | 10% |
Biochemistry, Genetics and Molecular Biology | 1 | 5% |
Unknown | 10 | 48% |