Title |
Advances in cancer pain from bone metastasis
|
---|---|
Published in |
Drug Design, Development and Therapy, August 2015
|
DOI | 10.2147/dddt.s87568 |
Pubmed ID | |
Authors |
Xiao-Cui Zhu, Jia-Li Zhang, Chen-Tao Ge, Yuan-Yang Yu, Pan Wang, Ti-Fei Yuan, Cai-Yun Fu |
Abstract |
With the technological advances in cancer diagnosis and treatment, the survival rates for patients with cancer are prolonged. The issue of figuring out how to improve the life quality of patients with cancer has become increasingly prominent. Pain, especially bone pain, is the most common symptom in malignancy patients, which seriously affects the life quality of patients with cancer. The research of cancer pain has a breakthrough due to the development of the animal models of cancer pain in recent years, such as the animal models of mouse femur, humerus, calcaneus, and rat tibia. The establishment of several kinds of animal models related to cancer pain provides a new platform in vivo to investigate the molecular mechanisms of cancer pain. In this review, we focus on the advances of cancer pain from bone metastasis, the mechanisms involved in cancer pain, and the drug treatment of cancer pain in the animal models. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 106 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 18 | 17% |
Student > Ph. D. Student | 10 | 9% |
Student > Master | 10 | 9% |
Researcher | 8 | 8% |
Student > Postgraduate | 8 | 8% |
Other | 15 | 14% |
Unknown | 37 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 25 | 24% |
Biochemistry, Genetics and Molecular Biology | 8 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 6% |
Neuroscience | 5 | 5% |
Agricultural and Biological Sciences | 4 | 4% |
Other | 19 | 18% |
Unknown | 39 | 37% |