Title |
Depression in people with type 2 diabetes: current perspectives
|
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Published in |
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, July 2018
|
DOI | 10.2147/dmso.s106797 |
Pubmed ID | |
Authors |
Lina Darwish, Erika Beroncal, Ma Veronica Sison, Walter Swardfager |
Abstract |
Type 2 diabetes mellitus (T2DM) is associated with depressive symptoms, and comorbid depression in those with T2DM has been associated with adverse clinical profiles. Recognizing and addressing psychological symptoms remain significant clinical challenges in T2DM. Possible mediators of the reciprocal relationship between T2DM and depression may include physical activity levels, effectiveness of self-management, distress associated with a new T2DM diagnosis, and frailty associated with advanced diabetes duration. The latter considerations contribute to a "J-shaped" trajectory from the time of diagnosis. There remain significant challenges to screening for clinical risks associated with psychological symptoms in T2DM; poorer outcomes may be associated with major depressive episodes, isolated (eg, anhedonic), or subsyndromal depressive symptoms, depressive-like symptoms more specific to T2DM (eg, diabetes-related distress), apathy or fatigue. In this review, we discuss current perspectives on depression in the context of T2DM with implications for screening and management of these highly comorbid conditions. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 14% |
United Kingdom | 1 | 14% |
Mexico | 1 | 14% |
India | 1 | 14% |
Unknown | 3 | 43% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 71% |
Practitioners (doctors, other healthcare professionals) | 2 | 29% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 287 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 38 | 13% |
Researcher | 33 | 11% |
Student > Bachelor | 29 | 10% |
Student > Ph. D. Student | 17 | 6% |
Student > Postgraduate | 15 | 5% |
Other | 37 | 13% |
Unknown | 118 | 41% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 64 | 22% |
Nursing and Health Professions | 25 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 13 | 5% |
Biochemistry, Genetics and Molecular Biology | 11 | 4% |
Psychology | 10 | 3% |
Other | 40 | 14% |
Unknown | 124 | 43% |