| Title |
Ocular manifestations and management recommendations of lysosomal storage disorders I: mucopolysaccharidoses
|
|---|---|
| Published in |
Clinical Ophthalmology, September 2015
|
| DOI | 10.2147/opth.s78368 |
| Pubmed ID | |
| Authors |
Carlton R Fenzl, Kyla Teramoto, Majid Moshirfar |
| Abstract |
The mucopolysaccharidoses (MPS) are a group of lysosomal storage disorders caused by inborn errors of glycosaminoglycan (GAG) metabolism. These diseases are classified by enzyme deficiency into seven groups: type I, II, III, IV, VI, VII, and IX. GAG accumulation leads to characteristic clinical features. Some ophthalmic findings that are characteristic of MPS diseases include corneal clouding, retinal degeneration, decreased electroretinogram wave amplitude, optic atrophy, papilledema, and glaucoma. Current treatments such as hematopoietic stem cell transplantation and enzyme replacement therapy have increased the life span of many MPS patients and created the need to improve management of ocular symptoms. This article aims to provide a comprehensive review of ocular manifestations and treatment options for the various types of MPS. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | 33% |
| United States | 1 | 17% |
| Italy | 1 | 17% |
| Australia | 1 | 17% |
| Unknown | 1 | 17% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 50% |
| Scientists | 2 | 33% |
| Practitioners (doctors, other healthcare professionals) | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 103 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Kazakhstan | 1 | <1% |
| Unknown | 102 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 15 | 15% |
| Student > Ph. D. Student | 10 | 10% |
| Student > Doctoral Student | 9 | 9% |
| Student > Master | 9 | 9% |
| Other | 8 | 8% |
| Other | 20 | 19% |
| Unknown | 32 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 30 | 29% |
| Agricultural and Biological Sciences | 11 | 11% |
| Biochemistry, Genetics and Molecular Biology | 9 | 9% |
| Engineering | 4 | 4% |
| Nursing and Health Professions | 3 | 3% |
| Other | 12 | 12% |
| Unknown | 34 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 September 2015.
All research outputs
#8,262,445
of 25,374,917 outputs
Outputs from Clinical Ophthalmology
#775
of 3,714 outputs
Outputs of similar age
#90,708
of 276,789 outputs
Outputs of similar age from Clinical Ophthalmology
#12
of 84 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 3,714 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,789 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.