↓ Skip to main content

Dove Medical Press

Article Metrics

Optical birefringence of liquid crystals for label-free optical biosensing diagnosis

Overview of attention for article published in International Journal of Nanomedicine, August 2015
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age

Mentioned by

twitter
1 tweeter

Citations

dimensions_citation
5 Dimensions

Readers on

mendeley
11 Mendeley
Title
Optical birefringence of liquid crystals for label-free optical biosensing diagnosis
Published in
International Journal of Nanomedicine, August 2015
DOI 10.2147/ijn.s88286
Pubmed ID
Authors

Seong Soo An, Tan Tai Nguyen, Gyeo-Re Han, Chang-Hyun Jang, Heongkyu Ju

Abstract

We present a polarization-sensitive optical detection platform for label-free quantitative optical biosensing diagnosis using liquid crystals (LCs). This is capable of determining quantitatively the optical birefringence of optical cells containing LCs, whose orientation depends on the immobilized biomolecules. This technique uses a polarization-dependent double-port detection without any polarizer at a single wavelength and removes the need of aligning optical cells of LCs in the azimuthal direction, with respect to the light path through the optical cell. Thus, this technique enables a stand-alone detection in a relatively compact format without an additional optical instrument, such as a retardation compensator, a Michael-Levy chart, and a spectrophotometer, in order to determine the optical birefringence quantitatively. We demonstrate that bovine serum albumin immobilized on the gold surface of the cell hybrid interfaces that support both homeotropic and planar anchoring of LCs causes optical phase retardation change which can be determined quantitatively. We also provide estimation of the zenithal orientation of LCs near the gold surface of the hybrid interfaces, based on the phase retardation determined. The estimated limit of bovine serum albumin detection is approximately 2.1 μM. This optical technique with LCs can serve an optical platform for label-free quantitative diagnosis of proteins in a real time manner.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 36%
Student > Ph. D. Student 3 27%
Researcher 1 9%
Professor 1 9%
Unknown 2 18%
Readers by discipline Count As %
Chemical Engineering 2 18%
Pharmacology, Toxicology and Pharmaceutical Science 2 18%
Physics and Astronomy 1 9%
Nursing and Health Professions 1 9%
Energy 1 9%
Other 3 27%
Unknown 1 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 September 2015.
All research outputs
#2,978,005
of 6,316,402 outputs
Outputs from International Journal of Nanomedicine
#864
of 1,513 outputs
Outputs of similar age
#105,357
of 194,912 outputs
Outputs of similar age from International Journal of Nanomedicine
#106
of 147 outputs
Altmetric has tracked 6,316,402 research outputs across all sources so far. This one is in the 30th percentile – i.e., 30% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,513 research outputs from this source. They receive a mean Attention Score of 1.8. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,912 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 147 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.