| Title |
Current perspectives on the health risks associated with the consumption of advanced glycation end products: recommendations for dietary management
|
|---|---|
| Published in |
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, September 2015
|
| DOI | 10.2147/dmso.s63089 |
| Pubmed ID | |
| Authors |
Sotiria Palimeri, Eleni Palioura, Evanthia Diamanti-Kandarakis |
| Abstract |
Advanced glycation end products (AGEs) constitute a complex group of compounds produced endogenously during the aging process and under conditions of hyperglycemia and oxidative stress. AGEs also have an emerging exogenous origin. Cigarette smoke and diet are the two main exogenous sources of AGEs (glycotoxins). Modern Western diets are rich in AGEs which have been implicated in the pathogenesis of several metabolic and degenerative disorders. Accumulating evidence underlies the beneficial effect of the dietary restriction of AGEs not only in animal studies but also in patients with diabetic complications and metabolic diseases. This article reviews the evidence linking dietary glycotoxins to several disorders from diabetic complications and renal failure to liver dysfunction, female reproduction, eye and cognitive disorders as well as cancer. Furthermore, strategies for AGE reduction are discussed with a focus on dietary modification. |
X Demographics
The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 33% |
| United Kingdom | 2 | 22% |
| Switzerland | 1 | 11% |
| Greece | 1 | 11% |
| Unknown | 2 | 22% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 44% |
| Practitioners (doctors, other healthcare professionals) | 3 | 33% |
| Scientists | 2 | 22% |
Mendeley readers
The data shown below were compiled from readership statistics for 136 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | <1% |
| Unknown | 135 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 23 | 17% |
| Student > Ph. D. Student | 20 | 15% |
| Student > Bachelor | 19 | 14% |
| Researcher | 14 | 10% |
| Student > Doctoral Student | 7 | 5% |
| Other | 20 | 15% |
| Unknown | 33 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 29 | 21% |
| Agricultural and Biological Sciences | 17 | 13% |
| Biochemistry, Genetics and Molecular Biology | 14 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 5% |
| Nursing and Health Professions | 6 | 4% |
| Other | 22 | 16% |
| Unknown | 41 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 March 2020.
All research outputs
#6,959,709
of 25,457,858 outputs
Outputs from Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
#278
of 1,184 outputs
Outputs of similar age
#74,375
of 276,962 outputs
Outputs of similar age from Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
#4
of 17 outputs
Altmetric has tracked 25,457,858 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 1,184 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.5. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,962 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.