Title |
Diagnostic and therapeutic considerations in idiopathic hypereosinophilia with warm autoimmune hemolytic anemia
|
---|---|
Published in |
Journal of Blood Medicine, September 2015
|
DOI | 10.2147/jbm.s90078 |
Pubmed ID | |
Authors |
Alexander J Sweidan, Adam K Brys, David D Sohn, Milan R Sheth |
Abstract |
Hypereosinophilic syndrome (HES) encompasses numerous diverse conditions resulting in peripheral hypereosinophilia that cannot be explained by hypersensitivity, infection, or atopy and that is not associated with known systemic diseases with specific organ involvement. HES is often attributed to neoplastic or reactive causes, such as chronic eosinophilic leukemia, although a majority of cases remains unexplained and are considered idiopathic. Here, we review the current diagnosis and management of HES and present a unique case of profound hypereosinophilia associated with warm autoimmune hemolytic anemia requiring intensive management. This case clearly illustrates the limitations of current knowledge with respect to hypereosinophilia syndrome as well as the challenges associated with its classification and management. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 10 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 3 | 30% |
Researcher | 3 | 30% |
Student > Master | 2 | 20% |
Student > Doctoral Student | 1 | 10% |
Professor > Associate Professor | 1 | 10% |
Other | 0 | 0% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 70% |
Immunology and Microbiology | 2 | 20% |
Biochemistry, Genetics and Molecular Biology | 1 | 10% |