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Validation study of the modified injection technique for internal mammary sentinel lymph node biopsy in breast cancer

Overview of attention for article published in OncoTargets and therapy, September 2015
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Title
Validation study of the modified injection technique for internal mammary sentinel lymph node biopsy in breast cancer
Published in
OncoTargets and therapy, September 2015
DOI 10.2147/ott.s91185
Pubmed ID
Authors

Bin-Bin Cong, Xiao-Shan Cao, Peng-Fei Qiu, Yan-Bing Liu, Tong Zhao, Peng Chen, Chun-Jian Wang, Zhao-Peng Zhang, Xiao Sun, Yong-Sheng Wang

Abstract

According to the hypothesis of internal mammary sentinel lymph node (IM-SLN) lymphatic drainage pattern, a modified radiotracer injection technique (periareolar intraparenchyma, high volume, and ultrasonographic guidance) was established. To verify the accuracy of the hypothesis and validate the modified radiotracer injection technique and to observe whether the lymphatic drainage of the whole breast parenchyma could reach to the same IM-SLN, different tracers were injected into different locations of the breast. The validation study results showed that the correlation and the agreement of the radiotracer and the fluorescence tracer are significant (case-base, r s =0.808, P<0.001; Kappa =0.79, P<0.001). It proved that the lymphatic drainage from different location of the breast (the primary tumor, the subareolar plexus) reached the same IM-SLNs and the hypothesis of IM-SLN lymphatic drainage pattern (ie, IM-SLN receives lymphatic drainage from not only the primary tumor area, but also the entire breast parenchyma). In other words, it validated the accuracy of our modified radiotracer injection technique.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 8%
Unknown 12 92%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 2 15%
Researcher 2 15%
Student > Master 2 15%
Professor 1 8%
Other 1 8%
Other 1 8%
Unknown 4 31%
Readers by discipline Count As %
Medicine and Dentistry 4 31%
Economics, Econometrics and Finance 2 15%
Nursing and Health Professions 1 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 8%
Agricultural and Biological Sciences 1 8%
Other 0 0%
Unknown 4 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 October 2015.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from OncoTargets and therapy
#2,078
of 3,016 outputs
Outputs of similar age
#237,474
of 276,788 outputs
Outputs of similar age from OncoTargets and therapy
#61
of 100 outputs
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So far Altmetric has tracked 3,016 research outputs from this source. They receive a mean Attention Score of 2.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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