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Altered regional homogeneity of spontaneous brain activity in idiopathic trigeminal neuralgia

Overview of attention for article published in Neuropsychiatric Disease and Treatment, October 2015
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (51st percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
4 tweeters
facebook
1 Facebook page

Citations

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26 Dimensions

Readers on

mendeley
48 Mendeley
Title
Altered regional homogeneity of spontaneous brain activity in idiopathic trigeminal neuralgia
Published in
Neuropsychiatric Disease and Treatment, October 2015
DOI 10.2147/ndt.s94877
Pubmed ID
Authors

Yanping Wang, Xiaoling Zhang, Qiaobing Guan, Lihong Wan, Yahui Yi, Chunfeng Liu

Abstract

The pathophysiology of idiopathic trigeminal neuralgia (ITN) has conventionally been thought to be induced by neurovascular compression theory. Recent structural brain imaging evidence has suggested an additional central component for ITN pathophysiology. However, far less attention has been given to investigations of the basis of abnormal resting-state brain activity in these patients. The objective of this study was to investigate local brain activity in patients with ITN and its correlation with clinical variables of pain. Resting-state functional magnetic resonance imaging data from 17 patients with ITN and 19 age- and sex-matched healthy controls were analyzed using regional homogeneity (ReHo) analysis, which is a data-driven approach used to measure the regional synchronization of spontaneous brain activity. Patients with ITN had decreased ReHo in the left amygdala, right parahippocampal gyrus, and left cerebellum and increased ReHo in the right inferior temporal gyrus, right thalamus, right inferior parietal lobule, and left postcentral gyrus (corrected). Furthermore, the increase in ReHo in the left precentral gyrus was positively correlated with visual analog scale (r=0.54; P=0.002). Our study found abnormal functional homogeneity of intrinsic brain activity in several regions in ITN, suggesting the maladaptivity of the process of daily pain attacks and a central role for the pathophysiology of ITN.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 48 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 23%
Student > Ph. D. Student 8 17%
Unspecified 4 8%
Student > Postgraduate 4 8%
Researcher 4 8%
Other 11 23%
Unknown 6 13%
Readers by discipline Count As %
Medicine and Dentistry 16 33%
Neuroscience 9 19%
Psychology 5 10%
Engineering 3 6%
Unspecified 2 4%
Other 3 6%
Unknown 10 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 October 2015.
All research outputs
#13,449,421
of 22,830,751 outputs
Outputs from Neuropsychiatric Disease and Treatment
#1,311
of 2,986 outputs
Outputs of similar age
#129,866
of 274,926 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#45
of 77 outputs
Altmetric has tracked 22,830,751 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,986 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.6. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,926 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.