| Title |
A review of the efficacy of mitomycin C in glaucoma filtration surgery
|
|---|---|
| Published in |
Clinical Ophthalmology, October 2015
|
| DOI | 10.2147/opth.s80111 |
| Pubmed ID | |
| Authors |
Ahmed Al Habash, Leyla Ali Aljasim, Ohoud Owaidhah, Deepak P Edward |
| Abstract |
The success of trabeculectomy, which is considered the gold standard in the surgical treatment of glaucoma, depends on the wound healing response. The introduction of antiproliferative agents such as mitomycin C (MMC) has increased the success rates of trabeculectomy. However, complications due to these agents can be challenging to manage. Hence, it is important to determine the most efficacious dose and duration of exposure. Multiple studies suggest that many factors, including but not limited to MMC preparation, different concentrations, different exposure times, and method of application may affect success rate, and these factors were reviewed in this article. We concluded that lower concentrations of MMC that are prepared and applied in a standardized fashion, such as that using the Mitosol(®) kit (for 2-3 minutes) during trabeculectomy, could potentially provide trabeculectomy success rates similar to that reported with off-label preparations, and that such a treatment regime could result in in lower complication rates than higher doses of MMC. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Russia | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 78 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 13 | 17% |
| Other | 11 | 14% |
| Student > Master | 8 | 10% |
| Student > Doctoral Student | 6 | 8% |
| Student > Bachelor | 6 | 8% |
| Other | 13 | 17% |
| Unknown | 21 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 31 | 40% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
| Biochemistry, Genetics and Molecular Biology | 3 | 4% |
| Social Sciences | 3 | 4% |
| Psychology | 2 | 3% |
| Other | 11 | 14% |
| Unknown | 24 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 October 2015.
All research outputs
#17,285,036
of 25,371,288 outputs
Outputs from Clinical Ophthalmology
#1,804
of 3,712 outputs
Outputs of similar age
#171,587
of 286,873 outputs
Outputs of similar age from Clinical Ophthalmology
#49
of 81 outputs
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